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Pancreatic ß cell microRNA-26a alleviates type 2 diabetes by improving peripheral insulin sensitivity and preserving ß cell function.
Xu, Haixia; Du, Xiao; Xu, Jia; Zhang, Yu; Tian, Yan; Liu, Geng; Wang, Xiuxuan; Ma, Meilin; Du, Wenya; Liu, Yu; Dai, Lunzhi; Huang, Wendong; Tong, Nanwei; Wei, Yuquan; Fu, Xianghui.
Affiliation
  • Xu H; Division of Endocrinology and Metabolism, National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.
  • Du X; Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, China.
  • Xu J; Department of General Surgery, Yaan People's Hospital, Yaan, Sichuan, China.
  • Zhang Y; Division of Endocrinology and Metabolism, National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.
  • Tian Y; Division of Endocrinology and Metabolism, National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.
  • Liu G; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.
  • Wang X; Division of Endocrinology and Metabolism, National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.
  • Ma M; Department of General Practice and Lab of PTM, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.
  • Du W; Division of Endocrinology and Metabolism, National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.
  • Liu Y; Division of Endocrinology and Metabolism, National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.
  • Dai L; Department of General Practice and Lab of PTM, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.
  • Huang W; Department of General Practice and Lab of PTM, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.
  • Tong N; Department of Diabetes Complications and Metabolism, Beckman Research Institute of City of Hope, Duarte, California, United States of America.
  • Wei Y; Division of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China.
  • Fu X; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, China.
PLoS Biol ; 18(2): e3000603, 2020 02.
Article in En | MEDLINE | ID: mdl-32092075
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Full text: 1 Database: MEDLINE Main subject: Insulin Resistance / MicroRNAs / Diabetes Mellitus, Type 2 / Insulin-Secreting Cells Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: PLoS Biol Journal subject: BIOLOGIA Year: 2020 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Insulin Resistance / MicroRNAs / Diabetes Mellitus, Type 2 / Insulin-Secreting Cells Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: PLoS Biol Journal subject: BIOLOGIA Year: 2020 Type: Article Affiliation country: China