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bioPROTACs as versatile modulators of intracellular therapeutic targets including proliferating cell nuclear antigen (PCNA).
Lim, Shuhui; Khoo, Regina; Peh, Khong Ming; Teo, Jinkai; Chang, Shih Chieh; Ng, Simon; Beilhartz, Greg L; Melnyk, Roman A; Johannes, Charles W; Brown, Christopher J; Lane, David P; Henry, Brian; Partridge, Anthony W.
Affiliation
  • Lim S; Quantitative Biosciences, MSD International, Singapore 138665.
  • Khoo R; Quantitative Biosciences, MSD International, Singapore 138665.
  • Peh KM; Quantitative Biosciences, MSD International, Singapore 138665.
  • Teo J; Pacific Translational Biomarkers, MSD International, Singapore 138665.
  • Chang SC; Quantitative Biosciences, MSD International, Singapore 138665.
  • Ng S; Quantitative Biosciences, MSD International, Singapore 138665.
  • Beilhartz GL; Molecular Medicine, Hospital for Sick Children, Toronto, ON, Canada M5G 0A4.
  • Melnyk RA; Molecular Medicine, Hospital for Sick Children, Toronto, ON, Canada M5G 0A4.
  • Johannes CW; Department of Biochemistry, University of Toronto, Toronto, ON, Canada M5S 1A8.
  • Brown CJ; p53Lab, Agency for Science, Technology and Research (A*STAR), Singapore 138648.
  • Lane DP; p53Lab, Agency for Science, Technology and Research (A*STAR), Singapore 138648.
  • Henry B; p53Lab, Agency for Science, Technology and Research (A*STAR), Singapore 138648.
  • Partridge AW; Quantitative Biosciences, MSD International, Singapore 138665.
Proc Natl Acad Sci U S A ; 117(11): 5791-5800, 2020 03 17.
Article in En | MEDLINE | ID: mdl-32123106
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Full text: 1 Database: MEDLINE Main subject: Protein Engineering / Proliferating Cell Nuclear Antigen / Ubiquitin-Protein Ligases / Proteolysis Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2020 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Protein Engineering / Proliferating Cell Nuclear Antigen / Ubiquitin-Protein Ligases / Proteolysis Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2020 Type: Article