Comparison of Patient-Oriented Eczema Measure and Patient-Oriented Scoring Atopic Dermatitis vs Eczema Area and Severity Index and other measures of atopic dermatitis: A validation study.
Ann Allergy Asthma Immunol
; 125(1): 78-83, 2020 07.
Article
in En
| MEDLINE
| ID: mdl-32199977
ABSTRACT
BACKGROUND:
Little is known about the measurement properties of Patient-Oriented Scoring Atopic Dermatitis (PO-SCORAD) in adults with atopic dermatitis (AD). Even less is known about how PO-SCORAD performs compared with the Patient-Oriented Eczema Measure (POEM).OBJECTIVE:
To examine the measurement properties of PO-SCORAD and compare them with those of POEM.METHODS:
A prospective dermatology practice-based study of 291 patients with AD (age range, 18-72 years).RESULTS:
PO-SCORAD and POEM were moderately correlated with each other (Spearman ρ = 0.56) and had weak-moderate correlations with the Numeric Rating Scale (NRS) worst itch and average itch, Dermatology Life Quality Index (DLQI), ItchyQOL, Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Disturbance (SD) and Sleep-Related Impairment (SRI), Patient Health Questionnaire-9 (PHQ-9), and Eczema Area and Severity Index (EASI) (P < .001). POEM had significantly stronger correlations with DLQI, ItchyQOL, and EASI than did PO-SCORAD. PO-SCORAD and POEM had fair discriminant validity. Changes from baseline in PO-SCORAD and POEM were moderately correlated with each other; were weakly to strongly correlated with NRS worst itch and average itch, DLQI, ItchyQOL, PROMIS SD, PROMIS SRI, PHQ-9, and EASI; and had good test-retest reliability. There was no differential item functioning of items or floor or ceiling effects for PO-SCORAD or POEM. The thresholds for meaningful change for PO-SCORAD and POEM were -15.5 and -5.0, respectively. Median completion times for PO-SCORAD and POEM were 3 minutes and 1 minute, respectively.CONCLUSION:
PO-SCORAD and POEM had good construct and cross-cultural validity, reliability, and responsiveness in adults with AD and were feasible for use in clinical trials and practice. However, POEM had better measurement properties than PO-SCORAD.
Full text:
1
Database:
MEDLINE
Main subject:
Severity of Illness Index
/
Dermatitis, Atopic
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Patient Reported Outcome Measures
Type of study:
Diagnostic_studies
Limits:
Adolescent
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Adult
/
Aged
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Female
/
Humans
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Male
/
Middle aged
Language:
En
Journal:
Ann Allergy Asthma Immunol
Journal subject:
ALERGIA E IMUNOLOGIA
Year:
2020
Type:
Article