Molecular Mechanisms of Facultative Heterochromatin Formation: An X-Chromosome Perspective.

Zylicz, Jan J; Heard, Edith

Zylicz, Jan J; Heard, Edith.

Affiliation

Zylicz JJ; Mammalian Developmental Epigenetics Group, Institut Curie, CNRS UMR 3215, INSERM U934, PSL University, 75248 Paris Cedex 05, France.
Heard E; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EL, United Kingdom.

Annu Rev Biochem ; 89: 255-282, 2020 06 20.

Article in En | MEDLINE | ID: mdl-32259458

Subject(s)

Gene Expression Regulation, Developmental; Genomic Imprinting; Heterochromatin/metabolism; Polycomb-Group Proteins/genetics; X Chromosome Inactivation; X Chromosome/metabolism; Animals; Chromatin Assembly and Disassembly; DNA-Binding Proteins/genetics; DNA-Binding Proteins/metabolism; Embryo, Mammalian; Female; Gene Silencing; Heterochromatin/chemistry; Histone Deacetylases/genetics; Histone Deacetylases/metabolism; Histones/genetics; Histones/metabolism; Humans; Male; Oocytes/cytology; Oocytes/growth & development; Oocytes/metabolism; Polycomb-Group Proteins/metabolism; RNA-Binding Proteins/genetics; RNA-Binding Proteins/metabolism; Spermatozoa/cytology; Spermatozoa/growth & development; Spermatozoa/metabolism; X Chromosome/chemistry

Key words

X-chromosome inactivation; development; epigenetics; facultative heterochromatin; noncoding RNA; stem cells

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Full text: 1 Database: MEDLINE Main subject: X Chromosome / Heterochromatin / Genomic Imprinting / Gene Expression Regulation, Developmental / X Chromosome Inactivation / Polycomb-Group Proteins Limits: Animals / Female / Humans / Male Language: En Journal: Annu Rev Biochem Year: 2020 Type: Article Affiliation country: France

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