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A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders.
Yang, Ka; Zhao, Yu; Nie, Xueqing; Wu, Hao; Wang, Bo; Almodovar-Rivera, Chelsi M; Xie, Haibo; Tang, Weiping.
Affiliation
  • Yang K; School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705, USA.
  • Zhao Y; School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705, USA.
  • Nie X; School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705, USA.
  • Wu H; School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705, USA.
  • Wang B; School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705, USA.
  • Almodovar-Rivera CM; School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705, USA.
  • Xie H; School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705, USA. Electronic address: hxie34@wisc.edu.
  • Tang W; School of Pharmacy, University of Wisconsin-Madison, Madison, WI 53705, USA; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53705, USA. Electronic address: weiping.tang@wisc.edu.
Cell Chem Biol ; 27(7): 866-876.e8, 2020 07 16.
Article in En | MEDLINE | ID: mdl-32413286
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Full text: 1 Database: MEDLINE Main subject: Ubiquitin-Protein Ligases / Adaptor Proteins, Signal Transducing / Histone Deacetylase 6 / Ligands Limits: Humans Language: En Journal: Cell Chem Biol Year: 2020 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Ubiquitin-Protein Ligases / Adaptor Proteins, Signal Transducing / Histone Deacetylase 6 / Ligands Limits: Humans Language: En Journal: Cell Chem Biol Year: 2020 Type: Article Affiliation country: United States