Ex vivo isolated human vessel perfusion system for the design and assessment of nanomedicines targeted to the endothelium.

Lysyy, Taras; Bracaglia, Laura G; Qin, Lingfeng; Albert, Claire; Pober, Jordan S; Tellides, George; Saltzman, W Mark; Tietjen, Gregory T

Lysyy, Taras; Bracaglia, Laura G; Qin, Lingfeng; Albert, Claire; Pober, Jordan S; Tellides, George; Saltzman, W Mark; Tietjen, Gregory T.

Affiliation

Lysyy T; Department of Surgery Yale School of Medicine New Haven Connecticut.
Bracaglia LG; Department of Biomedical Engineering Yale University New Haven Connecticut.
Qin L; Department of Surgery Yale School of Medicine New Haven Connecticut.
Albert C; Department of Biomedical Engineering Yale University New Haven Connecticut.
Pober JS; Department of Immunobiology Yale School of Medicine New Haven Connecticut.
Tellides G; Department of Surgery Yale School of Medicine New Haven Connecticut.
Saltzman WM; Department of Biomedical Engineering Yale University New Haven Connecticut.
Tietjen GT; Department of Chemical Engineering Yale University New Haven Connecticut.

Bioeng Transl Med ; 5(2): e10154, 2020 May.

Article in En | MEDLINE | ID: mdl-32440561

Key words

clinical translation; drug delivery systems; endothelial cell targeting; ex vivo perfusion; molecularly targeted therapies; nanoparticle accumulation; nanotechnology

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