Erxian decoction, a famous Chinese medicine formula, antagonizes corticosterone-induced injury in PC12 cells, and improves depression-like behaviours in mice.

Zhang, Lan; Yang, Yue; Di, Lei; Li, Jun-Long; Li, Ning

Zhang, Lan; Yang, Yue; Di, Lei; Li, Jun-Long; Li, Ning.

Affiliation

Zhang L; School of Pharmacy, Anhui Medical University, Hefei, PR China.
Yang Y; School of Pharmacy, Anhui Medical University, Hefei, PR China.
Di L; School of Pharmacy, Anhui Medical University, Hefei, PR China.
Li JL; School of Pharmacy, Anhui Medical University, Hefei, PR China.
Li N; School of Pharmacy, Anhui Medical University, Hefei, PR China.

Pharm Biol ; 58(1): 498-509, 2020 Dec.

Article in En | MEDLINE | ID: mdl-32476554

Subject(s)

Cell Survival/drug effects; Corticosterone/toxicity; Depression/drug therapy; Drugs, Chinese Herbal/therapeutic use; Medicine, Chinese Traditional; Animals; Cell Survival/physiology; Depression/psychology; Dose-Response Relationship, Drug; Drugs, Chinese Herbal/pharmacology; Male; Medicine, Chinese Traditional/methods; Mice; Mice, Inbred ICR; PC12 Cells; Rats

Key words

Neurotransmitter; behavioural test; cell apoptosis

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Full text: 1 Database: MEDLINE Main subject: Corticosterone / Drugs, Chinese Herbal / Cell Survival / Depression / Medicine, Chinese Traditional Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Pharm Biol Year: 2020 Type: Article

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