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Targeted Perturb-seq enables genome-scale genetic screens in single cells.
Schraivogel, Daniel; Gschwind, Andreas R; Milbank, Jennifer H; Leonce, Daniel R; Jakob, Petra; Mathur, Lukas; Korbel, Jan O; Merten, Christoph A; Velten, Lars; Steinmetz, Lars M.
Affiliation
  • Schraivogel D; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
  • Gschwind AR; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Milbank JH; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
  • Leonce DR; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
  • Jakob P; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
  • Mathur L; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
  • Korbel JO; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
  • Merten CA; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.
  • Velten L; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany. lars.velten@crg.eu.
  • Steinmetz LM; Center for Genomic Regulation, The Barcelona Institute of Science and Technology, Barcelona, Spain. lars.velten@crg.eu.
Nat Methods ; 17(6): 629-635, 2020 06.
Article in En | MEDLINE | ID: mdl-32483332
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Full text: 1 Database: MEDLINE Main subject: Genome, Human / Single-Cell Analysis / Transcriptome / Clustered Regularly Interspaced Short Palindromic Repeats / RNA-Seq Limits: Humans Language: En Journal: Nat Methods Journal subject: TECNICAS E PROCEDIMENTOS DE LABORATORIO Year: 2020 Type: Article Affiliation country: Germany
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Genome, Human / Single-Cell Analysis / Transcriptome / Clustered Regularly Interspaced Short Palindromic Repeats / RNA-Seq Limits: Humans Language: En Journal: Nat Methods Journal subject: TECNICAS E PROCEDIMENTOS DE LABORATORIO Year: 2020 Type: Article Affiliation country: Germany