Severe Refractory Checkpoint Inhibitor-Related Hepatitis Reversed With Anti-Thymocyte Globulin and n-Acetylcysteine.

Motomura, Douglas; Baetz, Tara; Grin, Andrea; Flemming, Jennifer A

Motomura, Douglas; Baetz, Tara; Grin, Andrea; Flemming, Jennifer A.

Affiliation

Motomura D; Department of Medicine, Queen's University, Kingston, Ontario, Canada.
Baetz T; Department of Oncology, Queen's University, Kingston, Ontario, Canada.
Grin A; Department of Pathology, Queen's University, Kingston, Ontario, Canada.
Flemming JA; Department of Medicine, Queen's University, Kingston, Ontario, Canada.

Hepatology ; 72(6): 2235-2238, 2020 12.

Article in En | MEDLINE | ID: mdl-32484945

Subject(s)

Acetylcysteine/therapeutic use; Antilymphocyte Serum/therapeutic use; Hepatitis/drug therapy; Immune Checkpoint Inhibitors/adverse effects; Immunosuppressive Agents/therapeutic use; Chemotherapy, Adjuvant/adverse effects; Chemotherapy, Adjuvant/methods; Drug Resistance; Drug Therapy, Combination/methods; Female; Glucocorticoids/therapeutic use; Hepatitis/diagnosis; Hepatitis/immunology; Humans; Melanoma/immunology; Melanoma/secondary; Melanoma/therapy; Middle Aged; Severity of Illness Index; Skin Neoplasms/immunology; Skin Neoplasms/pathology; Skin Neoplasms/therapy; Treatment Outcome

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Full text: 1 Database: MEDLINE Main subject: Acetylcysteine / Immune Checkpoint Inhibitors / Hepatitis / Immunosuppressive Agents / Antilymphocyte Serum Type of study: Diagnostic_studies Limits: Female / Humans / Middle aged Language: En Journal: Hepatology Year: 2020 Type: Article Affiliation country: Canada

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