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Towards human ex vivo organ perfusion models to elucidate drug pharmacokinetics in health and disease.
Stevens, Lianne J; Donkers, Joanne M; Dubbeld, Jeroen; Vaes, Wouter H J; Knibbe, Catherijne A J; Alwayn, Ian P J; van de Steeg, Evita.
Affiliation
  • Stevens LJ; Department of Surgery, Division of Transplantation, Leiden University Medical Centre (LUMC), Leiden, The Netherlands.
  • Donkers JM; The Netherlands Organisation for Applied Scientific Research (TNO), Zeist, The Netherlands.
  • Dubbeld J; The Netherlands Organisation for Applied Scientific Research (TNO), Zeist, The Netherlands.
  • Vaes WHJ; Department of Surgery, Division of Transplantation, Leiden University Medical Centre (LUMC), Leiden, The Netherlands.
  • Knibbe CAJ; The Netherlands Organisation for Applied Scientific Research (TNO), Zeist, The Netherlands.
  • Alwayn IPJ; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research (LACDR), Leiden, The Netherlands.
  • van de Steeg E; Department of Surgery, Division of Transplantation, Leiden University Medical Centre (LUMC), Leiden, The Netherlands.
Drug Metab Rev ; 52(3): 438-454, 2020 08.
Article in En | MEDLINE | ID: mdl-32551945
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Full text: 1 Database: MEDLINE Main subject: Pharmacokinetics / Pharmaceutical Preparations / Drug Evaluation, Preclinical / Liver / Models, Biological Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Drug Metab Rev Year: 2020 Type: Article Affiliation country: Netherlands
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Pharmacokinetics / Pharmaceutical Preparations / Drug Evaluation, Preclinical / Liver / Models, Biological Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Drug Metab Rev Year: 2020 Type: Article Affiliation country: Netherlands