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Liver X Receptor Alpha Activation Inhibits Autophagy and Lipophagy in Hepatocytes by Dysregulating Autophagy-Related 4B Cysteine Peptidase and Rab-8B, Reducing Mitochondrial Fuel Oxidation.
Kim, Yun Seok; Nam, Hyeon Joo; Han, Chang Yeob; Joo, Min Sung; Jang, Kiseok; Jun, Dae Won; Kim, Sang Geon.
Affiliation
  • Kim YS; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Korea.
  • Nam HJ; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Korea.
  • Han CY; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Korea.
  • Joo MS; School of Pharmacy, Jeonbuk National University, Jeonju-si, Jeonbuk, Korea.
  • Jang K; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Korea.
  • Jun DW; Department of Pathology, Hanyang University School of Medicine, Seoul, Korea.
  • Kim SG; Internal Medicine, Hanyang University School of Medicine, Seoul, Korea.
Hepatology ; 73(4): 1307-1326, 2021 04.
Article in En | MEDLINE | ID: mdl-32557804
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Full text: 1 Database: MEDLINE Main subject: Autophagy / Cysteine Endopeptidases / Rab GTP-Binding Proteins / Hepatocytes / Autophagy-Related Proteins / Liver X Receptors / Mitochondria Type of study: Etiology_studies / Prognostic_studies Language: En Journal: Hepatology Year: 2021 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Autophagy / Cysteine Endopeptidases / Rab GTP-Binding Proteins / Hepatocytes / Autophagy-Related Proteins / Liver X Receptors / Mitochondria Type of study: Etiology_studies / Prognostic_studies Language: En Journal: Hepatology Year: 2021 Type: Article