An agent-based model of prostate Cancer bone metastasis progression and response to Radium223.

Casarin, Stefano; Dondossola, Eleonora

Casarin, Stefano; Dondossola, Eleonora.

Affiliation

Casarin S; Center for Computational Surgery, Houston Methodist Research Institute, Houston, TX, USA. scasarin@houstonmethodist.org.
Dondossola E; Department of Surgery, Houston Methodist Hospital, Houston, TX, USA. scasarin@houstonmethodist.org.

BMC Cancer ; 20(1): 605, 2020 Jun 29.

Article in En | MEDLINE | ID: mdl-32600282

Subject(s)

Bone Neoplasms/radiotherapy; Brachytherapy/methods; Models, Biological; Prostatic Neoplasms/pathology; Radium/administration & dosage; Animals; Bone Neoplasms/diagnosis; Bone Neoplasms/secondary; Cell Line, Tumor; Computer Simulation; Disease Progression; Humans; Intravital Microscopy; Male; Mice; Microscopy, Fluorescence; Prostatic Neoplasms/radiotherapy; Radiation Tolerance; Tibia/diagnostic imaging; Tibia/pathology; Tibia/radiation effects; Xenograft Model Antitumor Assays

Key words

In silico model; Prostate cancer bone metastasis; Radium 223; Therapy optimization; Therapy response; Tumor growth

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Full text: 1 Database: MEDLINE Main subject: Prostatic Neoplasms / Bone Neoplasms / Brachytherapy / Radium / Models, Biological Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: BMC Cancer Journal subject: NEOPLASIAS Year: 2020 Type: Article Affiliation country: United States

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