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Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK ß1 isoforms.
Pinkosky, Stephen L; Scott, John W; Desjardins, Eric M; Smith, Brennan K; Day, Emily A; Ford, Rebecca J; Langendorf, Christopher G; Ling, Naomi X Y; Nero, Tracy L; Loh, Kim; Galic, Sandra; Hoque, Ashfaqul; Smiles, William J; Ngoei, Kevin R W; Parker, Michael W; Yan, Yan; Melcher, Karsten; Kemp, Bruce E; Oakhill, Jonathan S; Steinberg, Gregory R.
Affiliation
  • Pinkosky SL; Centre for Metabolism, Obesity and Diabetes Research and the Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
  • Scott JW; Protein Chemistry & Metabolism, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.
  • Desjardins EM; Mary MacKillop Institute for Health Research, Australian Catholic University, Fitzroy, Victoria, Australia.
  • Smith BK; The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia.
  • Day EA; Centre for Metabolism, Obesity and Diabetes Research and the Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
  • Ford RJ; Centre for Metabolism, Obesity and Diabetes Research and the Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
  • Langendorf CG; Centre for Metabolism, Obesity and Diabetes Research and the Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
  • Ling NXY; Centre for Metabolism, Obesity and Diabetes Research and the Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
  • Nero TL; Protein Chemistry & Metabolism, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.
  • Loh K; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.
  • Galic S; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.
  • Hoque A; Structural Biology and Computational Design Laboratory, Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria, Australia.
  • Smiles WJ; Protein Chemistry & Metabolism, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.
  • Ngoei KRW; Protein Chemistry & Metabolism, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.
  • Parker MW; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.
  • Yan Y; Metabolic Signalling Laboratory, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.
  • Melcher K; Protein Chemistry & Metabolism, St Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.
  • Kemp BE; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, School of Medicine, University of Melbourne, Fitzroy, Victoria, Australia.
  • Oakhill JS; Structural Biology and Computational Design Laboratory, Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria, Australia.
  • Steinberg GR; Center for Cancer and Cell Biology, Structural Biology Program, Van Andel Research Institute, Grand Rapids, MI, USA.
Nat Metab ; 2(9): 873-881, 2020 09.
Article in En | MEDLINE | ID: mdl-32719536
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Full text: 1 Database: MEDLINE Main subject: Acyl Coenzyme A / Allosteric Regulation / AMP-Activated Protein Kinases Limits: Animals Language: En Journal: Nat Metab Year: 2020 Type: Article Affiliation country: Canada
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Full text: 1 Database: MEDLINE Main subject: Acyl Coenzyme A / Allosteric Regulation / AMP-Activated Protein Kinases Limits: Animals Language: En Journal: Nat Metab Year: 2020 Type: Article Affiliation country: Canada