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Plasma p-tau181 accurately predicts Alzheimer's disease pathology at least 8 years prior to post-mortem and improves the clinical characterisation of cognitive decline.
Lantero Rodriguez, Juan; Karikari, Thomas K; Suárez-Calvet, Marc; Troakes, Claire; King, Andrew; Emersic, Andreja; Aarsland, Dag; Hye, Abdul; Zetterberg, Henrik; Blennow, Kaj; Ashton, Nicholas J.
Affiliation
  • Lantero Rodriguez J; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
  • Karikari TK; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
  • Suárez-Calvet M; Barcelonaßeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.
  • Troakes C; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.
  • King A; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain.
  • Emersic A; Servei de Neurologia, Hospital del Mar, Barcelona, Spain.
  • Aarsland D; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
  • Hye A; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
  • Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
  • Blennow K; Department of Neurology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
  • Ashton NJ; Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Acta Neuropathol ; 140(3): 267-278, 2020 09.
Article in En | MEDLINE | ID: mdl-32720099
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Full text: 1 Database: MEDLINE Main subject: Biomarkers / Tau Proteins / Early Diagnosis / Alzheimer Disease Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Humans Language: En Journal: Acta Neuropathol Year: 2020 Type: Article Affiliation country: Sweden
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Biomarkers / Tau Proteins / Early Diagnosis / Alzheimer Disease Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Humans Language: En Journal: Acta Neuropathol Year: 2020 Type: Article Affiliation country: Sweden