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Effects of Interleukin-1ß Inhibition on Incident Hip and Knee Replacement : Exploratory Analyses From a Randomized, Double-Blind, Placebo-Controlled Trial.
Schieker, Matthias; Conaghan, Philip G; Mindeholm, Linda; Praestgaard, Jens; Solomon, Daniel H; Scotti, Celeste; Gram, Herman; Thuren, Tom; Roubenoff, Ronenn; Ridker, Paul M.
Affiliation
  • Schieker M; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, and Basel, Switzerland, and Ludwig Maximilian University of Munich, Munich, Germany (M.S.).
  • Conaghan PG; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research Leeds BiomedicalResearch Centre, Leeds, United Kingdom (P.G.C.).
  • Mindeholm L; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, and Basel, Switzerland (L.M., J.P., C.S., H.G., R.R.).
  • Praestgaard J; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, and Basel, Switzerland (L.M., J.P., C.S., H.G., R.R.).
  • Solomon DH; Brigham and Women's Hospital, Boston, Massachusetts (D.H.S., P.M.R.).
  • Scotti C; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, and Basel, Switzerland (L.M., J.P., C.S., H.G., R.R.).
  • Gram H; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, and Basel, Switzerland (L.M., J.P., C.S., H.G., R.R.).
  • Thuren T; Novartis Pharma AG, Basel, Switzerland (T.T.).
  • Roubenoff R; Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, and Basel, Switzerland (L.M., J.P., C.S., H.G., R.R.).
  • Ridker PM; Brigham and Women's Hospital, Boston, Massachusetts (D.H.S., P.M.R.).
Ann Intern Med ; 173(7): 509-515, 2020 10 06.
Article in En | MEDLINE | ID: mdl-32744862
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Full text: 1 Database: MEDLINE Main subject: Osteoarthritis, Hip / Arthroplasty, Replacement, Hip / Arthroplasty, Replacement, Knee / Osteoarthritis, Knee / Interleukin-18 / Antibodies, Monoclonal, Humanized Type of study: Clinical_trials / Incidence_studies / Prognostic_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: Ann Intern Med Year: 2020 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Osteoarthritis, Hip / Arthroplasty, Replacement, Hip / Arthroplasty, Replacement, Knee / Osteoarthritis, Knee / Interleukin-18 / Antibodies, Monoclonal, Humanized Type of study: Clinical_trials / Incidence_studies / Prognostic_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: Ann Intern Med Year: 2020 Type: Article