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Atazanavir, Alone or in Combination with Ritonavir, Inhibits SARS-CoV-2 Replication and Proinflammatory Cytokine Production.
Fintelman-Rodrigues, Natalia; Sacramento, Carolina Q; Ribeiro Lima, Carlyle; Souza da Silva, Franklin; Ferreira, André C; Mattos, Mayara; de Freitas, Caroline S; Cardoso Soares, Vinicius; da Silva Gomes Dias, Suelen; Temerozo, Jairo R; Miranda, Milene D; Matos, Aline R; Bozza, Fernando A; Carels, Nicolas; Alves, Carlos Roberto; Siqueira, Marilda M; Bozza, Patrícia T; Souza, Thiago Moreno L.
Affiliation
  • Fintelman-Rodrigues N; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.
  • Sacramento CQ; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Ribeiro Lima C; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.
  • Souza da Silva F; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Ferreira AC; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Mattos M; Laboratório de Biologia Molecular e Doenças Endêmicas, IOC, Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • de Freitas CS; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Cardoso Soares V; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.
  • da Silva Gomes Dias S; Universidade Iguaçu, Nova Iguaçu, Rio de Janeiro, Brazil.
  • Temerozo JR; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Miranda MD; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.
  • Matos AR; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Bozza FA; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.
  • Carels N; National Institute for Science and Technology on Innovation in Diseases of Neglected Populations (INCT/IDPN), Center for Technological Development in Health (CDTS), Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Alves CR; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.
  • Siqueira MM; Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz (IOC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Rio de Janeiro, Brazil.
  • Bozza PT; Laboratório de Pesquisas sobre o Timo, IOC, Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Souza TML; National Institute for Science and Technology on Neuroimmunomodulation (INCT/NIM), IOC, Fiocruz, Rio de Janeiro, Rio de Janeiro, Brazil.
Antimicrob Agents Chemother ; 64(10)2020 09 21.
Article in En | MEDLINE | ID: mdl-32759267
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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / Cytokines / Ritonavir / Atazanavir Sulfate / Betacoronavirus Type of study: Prognostic_studies Language: En Journal: Antimicrob Agents Chemother Year: 2020 Type: Article Affiliation country: Brazil
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / Cytokines / Ritonavir / Atazanavir Sulfate / Betacoronavirus Type of study: Prognostic_studies Language: En Journal: Antimicrob Agents Chemother Year: 2020 Type: Article Affiliation country: Brazil