Astrocyte DISC1 contributes to cognitive function in a brain region-dependent manner.

Shevelkin, Alexey V; Terrillion, Chantelle E; Hasegawa, Yuto; Mychko, Olga A; Jouroukhin, Yan; Sawa, Akira; Kamiya, Atsushi; Pletnikov, Mikhail V

Shevelkin, Alexey V; Terrillion, Chantelle E; Hasegawa, Yuto; Mychko, Olga A; Jouroukhin, Yan; Sawa, Akira; Kamiya, Atsushi; Pletnikov, Mikhail V.

Affiliation

Shevelkin AV; Departments of Psychiatry and Behavioral Sciences.
Terrillion CE; Departments of Psychiatry and Behavioral Sciences.
Hasegawa Y; Departments of Psychiatry and Behavioral Sciences.
Mychko OA; Departments of Psychiatry and Behavioral Sciences.
Jouroukhin Y; Departments of Psychiatry and Behavioral Sciences.
Sawa A; Departments of Psychiatry and Behavioral Sciences.
Kamiya A; Solomon H. Snyder Department of Neuroscience.
Pletnikov MV; Department of Biomedical Engineering.

Hum Mol Genet ; 29(17): 2936-2950, 2020 10 10.

Article in En | MEDLINE | ID: mdl-32803234

Subject(s)

Brain/metabolism; Cognition/physiology; Nerve Degeneration/genetics; Nerve Tissue Proteins/genetics; Animals; Astrocytes/metabolism; Astrocytes/pathology; Brain/pathology; Brain Mapping; Deep Learning; Gene Knockdown Techniques; Hippocampus/metabolism; Hippocampus/pathology; Humans; Mice; Nerve Degeneration/metabolism; Nerve Degeneration/pathology; Nerve Net/pathology; Neuroglia/metabolism; Neuroglia/pathology; Prefrontal Cortex/metabolism; Prefrontal Cortex/pathology

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Full text: 1 Database: MEDLINE Main subject: Brain / Cognition / Nerve Degeneration / Nerve Tissue Proteins Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2020 Type: Article

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