Hsf1 on a leash - controlling the heat shock response by chaperone titration.

Masser, Anna E; Ciccarelli, Michela; Andréasson, Claes

Masser, Anna E; Ciccarelli, Michela; Andréasson, Claes.

Affiliation

Masser AE; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, S-106 91, Stockholm, Sweden.
Ciccarelli M; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, S-106 91, Stockholm, Sweden.
Andréasson C; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, S-106 91, Stockholm, Sweden. Electronic address: claes.andreasson@su.se.

Exp Cell Res ; 396(1): 112246, 2020 11 01.

Article in En | MEDLINE | ID: mdl-32861670

Subject(s)

HSP70 Heat-Shock Proteins/metabolism; HSP90 Heat-Shock Proteins/metabolism; Heat Shock Transcription Factors/metabolism; Neoplasms/metabolism; Neurodegenerative Diseases/metabolism; Protein Processing, Post-Translational; Acylation; Feedback, Physiological; HSP70 Heat-Shock Proteins/genetics; HSP90 Heat-Shock Proteins/genetics; Heat Shock Transcription Factors/genetics; Heat-Shock Response/genetics; Homeostasis/genetics; Humans; Neoplasms/genetics; Neoplasms/pathology; Neurodegenerative Diseases/genetics; Neurodegenerative Diseases/pathology; Phosphorylation; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/metabolism; Saccharomyces cerevisiae Proteins/genetics; Saccharomyces cerevisiae Proteins/metabolism; Signal Transduction; Ubiquitination

Key words

Heat shock factor 1; Heat shock response; Hsp70; Hsp90; Misfolded proteins; Protein homeostasis

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Full text: 1 Database: MEDLINE Main subject: Protein Processing, Post-Translational / HSP90 Heat-Shock Proteins / HSP70 Heat-Shock Proteins / Neurodegenerative Diseases / Heat Shock Transcription Factors / Neoplasms Limits: Humans Language: En Journal: Exp Cell Res Year: 2020 Type: Article Affiliation country: Sweden

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