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The Polygenic and Monogenic Basis of Blood Traits and Diseases.
Vuckovic, Dragana; Bao, Erik L; Akbari, Parsa; Lareau, Caleb A; Mousas, Abdou; Jiang, Tao; Chen, Ming-Huei; Raffield, Laura M; Tardaguila, Manuel; Huffman, Jennifer E; Ritchie, Scott C; Megy, Karyn; Ponstingl, Hannes; Penkett, Christopher J; Albers, Patrick K; Wigdor, Emilie M; Sakaue, Saori; Moscati, Arden; Manansala, Regina; Lo, Ken Sin; Qian, Huijun; Akiyama, Masato; Bartz, Traci M; Ben-Shlomo, Yoav; Beswick, Andrew; Bork-Jensen, Jette; Bottinger, Erwin P; Brody, Jennifer A; van Rooij, Frank J A; Chitrala, Kumaraswamy N; Wilson, Peter W F; Choquet, Hélène; Danesh, John; Di Angelantonio, Emanuele; Dimou, Niki; Ding, Jingzhong; Elliott, Paul; Esko, Tõnu; Evans, Michele K; Felix, Stephan B; Floyd, James S; Broer, Linda; Grarup, Niels; Guo, Michael H; Guo, Qi; Greinacher, Andreas; Haessler, Jeff; Hansen, Torben; Howson, Joanna M M; Huang, Wei.
Affiliation
  • Vuckovic D; Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK; National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK.
  • Bao EL; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA; Harvard-MIT Health Sciences and Technology, Harvard Medical S
  • Akbari P; Department of Public Health and Primary Care, British Heart Foundation Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB1 8RN, UK; National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, University of Cambridge, Cambr
  • Lareau CA; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
  • Mousas A; Montreal Heart Institute, Montreal, Quebec, H1T 1C8, Canada.
  • Jiang T; Department of Public Health and Primary Care, British Heart Foundation Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB1 8RN, UK; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge
  • Chen MH; The Framingham Heart Study, National Heart, Lung and Blood Institute, Framingham, MA, 01702, USA; Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, MA, 01702, USA.
  • Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA.
  • Tardaguila M; Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.
  • Huffman JE; Center for Population Genomics, Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, 02130, USA.
  • Ritchie SC; Department of Public Health and Primary Care, Cambridge Baker Systems Genomics Initiative, University of Cambridge, Cambridge, CB1 8RN, UK; Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute, Melbourne, Victoria, VIC 3004, Australia; Department of Public Health and Prima
  • Megy K; Department of Haematology, University of Cambridge, Cambridge, CB2 0PT, UK; National Institute for Health Research (NIHR) BioResource, Cambridge University Hospitals, Cambridge, CB2 0PT, UK; National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge, CB2 0PT, UK.
  • Ponstingl H; Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.
  • Penkett CJ; National Institute for Health Research (NIHR) BioResource, Cambridge University Hospitals, Cambridge, CB2 0PT, UK; Department of Haematology, University of Cambridge, Cambridge, CB2 0PT, UK.
  • Albers PK; Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.
  • Wigdor EM; Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.
  • Sakaue S; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan.
  • Moscati A; Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, NY, 10029, USA.
  • Manansala R; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, 53201, USA.
  • Lo KS; Montreal Heart Institute, Montreal, Quebec, H1T 1C8, Canada.
  • Qian H; Department of Statistics and Operation Research, University of North Carolina, Chapel Hill, NC, 27599, USA.
  • Akiyama M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan; Department of Ocular Pathology and Imaging Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8581, Japan.
  • Bartz TM; Department of Biostatistics, University of Washington, Seattle, WA, 98101, USA.
  • Ben-Shlomo Y; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1QU, UK.
  • Beswick A; Translational Health Sciences, Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, Bristol, BS10 5NB, UK.
  • Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark.
  • Bottinger EP; Hasso-Plattner-Institut, Universität Potsdam, Potsdam, 14469, Germany; Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, NY, 10029, USA.
  • Brody JA; Department of Medicine, University of Washington, Seattle, WA, 98101, USA.
  • van Rooij FJA; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, 3015 GE, the Netherlands.
  • Chitrala KN; Laboratory of Epidemiology and Population Science, National Institute on Aging/NIH, Baltimore, MD, 21224, USA.
  • Wilson PWF; Atlanta VA Medical Center, Decatur, GA, 30033, USA.
  • Choquet H; Division of Research, Kaiser Permanente Northern California, Oakland, CA, 94612, USA.
  • Danesh J; Department of Public Health and Primary Care, British Heart Foundation Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB1 8RN, UK; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB10 1SA, UK; National Institute for Health Rese
  • Di Angelantonio E; Department of Public Health and Primary Care, British Heart Foundation Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB1 8RN, UK; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB10 1SA, UK; National Institute for Health Rese
  • Dimou N; Section of Nutrition and Metabolism, International Agency for Research on Cancer, Lyon, 69008, France; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, 45110, Greece.
  • Ding J; Department of Internal Medicine, Section of Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27101, USA.
  • Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK; Imperial Biomedical Research Centre, Imperial College London and Imperial College NHS Healthcare Trust, London, W2 1NY, UK; Medical Research Council Centre for Environment and Health, Imperial College London,
  • Esko T; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
  • Evans MK; Laboratory of Epidemiology and Population Science, National Institute on Aging/NIH, Baltimore, MD, 21224, USA.
  • Felix SB; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, 17475, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Greifswald, Greifswald, 17475, Germany.
  • Floyd JS; Department of Medicine, University of Washington, Seattle, WA, 98101, USA; Department of Epidemiology, University of Washington, Seattle, WA, 98101, USA.
  • Broer L; Department of Internal Medicine, Erasmus University Medical Center Rotterdam, Rotterdam, 3015 GE, the Netherlands.
  • Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark.
  • Guo MH; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA; Department of Neurology, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Guo Q; Department of Public Health and Primary Care, British Heart Foundation Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB1 8RN, UK.
  • Greinacher A; Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald, 17475, Germany.
  • Haessler J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98101, USA.
  • Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark.
  • Howson JMM; Department of Public Health and Primary Care, British Heart Foundation Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB1 8RN, UK; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge
  • Huang W; Department of Genetics, Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center and Shanghai Industrial Technology Institute (SITI), Shanghai, 201203, China.
Cell ; 182(5): 1214-1231.e11, 2020 09 03.
Article in En | MEDLINE | ID: mdl-32888494

Full text: 1 Database: MEDLINE Main subject: Genetic Predisposition to Disease / Multifactorial Inheritance Type of study: Prognostic_studies / Systematic_reviews Limits: Female / Humans / Male Language: En Journal: Cell Year: 2020 Type: Article Affiliation country: United kingdom

Full text: 1 Database: MEDLINE Main subject: Genetic Predisposition to Disease / Multifactorial Inheritance Type of study: Prognostic_studies / Systematic_reviews Limits: Female / Humans / Male Language: En Journal: Cell Year: 2020 Type: Article Affiliation country: United kingdom