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Impact of enantiomer-specific changes in pharmacokinetics between infants and adults on the target concentration of racemic ketorolac: A pooled analysis.
Cloesmeijer, Michael E; van Esdonk, Michiel J; Lynn, Anne M; Smits, Anne; Tibboel, Dick; Daali, Youssef; Olkkola, Klaus T; Allegaert, Karel; Mian, Paola.
Affiliation
  • Cloesmeijer ME; Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
  • van Esdonk MJ; Department of Hospital Pharmacy - Clinical Pharmacology, Amsterdam University Medical Centres, Amsterdam, The Netherlands.
  • Lynn AM; Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
  • Smits A; Centre for Human Drug Research, Leiden, The Netherlands.
  • Tibboel D; Department of Anesthesiology & Pain Medicine, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, WA, USA.
  • Daali Y; Neonatal Intensive Care Unit, University Hospitals Leuven, Leuven, Belgium.
  • Olkkola KT; Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
  • Allegaert K; Intensive Care and Department of Paediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands.
  • Mian P; Division of Clinical Pharmacology and Toxicology, Geneva University Hospitals, Geneva, Switzerland.
Br J Clin Pharmacol ; 87(3): 1443-1454, 2021 03.
Article in En | MEDLINE | ID: mdl-32901947
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Full text: 1 Database: MEDLINE Main subject: Pharmaceutical Preparations / Ketorolac Type of study: Prognostic_studies / Systematic_reviews Limits: Adult / Child / Humans / Infant Language: En Journal: Br J Clin Pharmacol Year: 2021 Type: Article Affiliation country: Netherlands
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Pharmaceutical Preparations / Ketorolac Type of study: Prognostic_studies / Systematic_reviews Limits: Adult / Child / Humans / Infant Language: En Journal: Br J Clin Pharmacol Year: 2021 Type: Article Affiliation country: Netherlands