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Development and validation of a novel immunogenicity assay to detect anti-drug and anti-PEG antibodies simultaneously with high sensitivity.
Bivi, Nicoletta; Swearingen, Craig A; Shockley, Travis E; Sloan, John H; Pottanat, Thomas G; Carter, Quincy Lasha; Hodsdon, Michael E; Siegel, Robert W; Konrad, Robert J.
Affiliation
  • Bivi N; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States of America. Electronic address: bivi_nicoletta@lilly.com.
  • Swearingen CA; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States of America.
  • Shockley TE; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States of America.
  • Sloan JH; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States of America.
  • Pottanat TG; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States of America.
  • Carter QL; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States of America.
  • Hodsdon ME; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States of America.
  • Siegel RW; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States of America.
  • Konrad RJ; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, United States of America.
J Immunol Methods ; 486: 112856, 2020 11.
Article in En | MEDLINE | ID: mdl-32916164
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Full text: 1 Database: MEDLINE Main subject: Polyethylene Glycols / Biological Products / Recombinant Proteins / Immunoglobulin M / Immunoassay / Excipients Type of study: Diagnostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: J Immunol Methods Year: 2020 Type: Article
Fulltext
Add to My VHL
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Full text: 1 Database: MEDLINE Main subject: Polyethylene Glycols / Biological Products / Recombinant Proteins / Immunoglobulin M / Immunoassay / Excipients Type of study: Diagnostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: J Immunol Methods Year: 2020 Type: Article