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Gut Microbes' Impact on Oncogenic Drivers: Location Matters.
White, Michael G; Wargo, Jennifer A.
Affiliation
  • White MG; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Wargo JA; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: jwargo@mdanderson.org.
Mol Cell ; 79(6): 878-880, 2020 09 17.
Article in En | MEDLINE | ID: mdl-32946762
ABSTRACT
Recent work by Kadosh et al. (2020) suggests that mutant p53 activity in gut epithelia is influenced by local production of microbial metabolites. The switch of p53 from tumor suppressor to oncogene is location-dependent and is impacted by microbially derived gallic acid.
Subject(s)

Full text: 1 Database: MEDLINE Main subject: Gastrointestinal Microbiome Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2020 Type: Article Affiliation country: United States

Full text: 1 Database: MEDLINE Main subject: Gastrointestinal Microbiome Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2020 Type: Article Affiliation country: United States