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A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors.
Barnoud, Thibaut; Leung, Jessica C; Leu, Julia I-Ju; Basu, Subhasree; Poli, Adi Narayana Reddy; Parris, Joshua L D; Indeglia, Alexandra; Martynyuk, Tetyana; Good, Madeline; Gnanapradeepan, Keerthana; Sanseviero, Emilio; Moeller, Rebecca; Tang, Hsin-Yao; Cassel, Joel; Kossenkov, Andrew V; Liu, Qin; Speicher, David W; Gabrilovich, Dmitry I; Salvino, Joseph M; George, Donna L; Murphy, Maureen E.
Affiliation
  • Barnoud T; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Leung JC; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Leu JI; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Basu S; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Poli ANR; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Parris JLD; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Indeglia A; Department of Graduate Group in Cell and Molecular Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Martynyuk T; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Good M; Department of Biochemistry and Molecular Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Gnanapradeepan K; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Sanseviero E; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Moeller R; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Tang HY; Department of Biochemistry and Molecular Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Cassel J; Program in Immunology, Metastasis and Microenvironment, The Wistar Institute, Philadelphia, Pennsylvania.
  • Kossenkov AV; Drexel University College of Medicine, Philadelphia, Pennsylvania.
  • Liu Q; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Speicher DW; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Gabrilovich DI; Program in Gene Expression and Regulation, The Wistar Institute, Philadelphia, Pennsylvania.
  • Salvino JM; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • George DL; Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, Pennsylvania.
  • Murphy ME; Department of Graduate Group in Cell and Molecular Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Cancer Res ; 80(23): 5270-5281, 2020 12 01.
Article in En | MEDLINE | ID: mdl-33023943
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Full text: 1 Database: MEDLINE Main subject: Colorectal Neoplasms / HSP70 Heat-Shock Proteins / Mitochondria / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Cancer Res Year: 2020 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Colorectal Neoplasms / HSP70 Heat-Shock Proteins / Mitochondria / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Cancer Res Year: 2020 Type: Article