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sPLA2-IB and PLA2R mediate insufficient autophagy and contribute to podocyte injury in idiopathic membranous nephropathy by activation of the p38MAPK/mTOR/ULK1ser757 signaling pathway.
Yang, Liyan; Wu, Yuansheng; Lin, Songhua; Dai, Binbin; Chen, Hong; Tao, Xuan; Li, Guoping; Wan, Jianxin; Pan, Yangbin.
Affiliation
  • Yang L; Department of Nephrology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
  • Wu Y; Department of Cardiology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
  • Lin S; Department of Nephrology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
  • Dai B; Department of Nephrology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
  • Chen H; Department of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
  • Tao X; Department of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
  • Li G; Department of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
  • Wan J; Department of Nephrology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
  • Pan Y; Department of Nephrology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
FASEB J ; 35(2): e21170, 2021 02.
Article in En | MEDLINE | ID: mdl-33184968
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Full text: 1 Database: MEDLINE Main subject: Autophagy / Glomerulonephritis, Membranous / MAP Kinase Signaling System / P38 Mitogen-Activated Protein Kinases / Intracellular Signaling Peptides and Proteins / Podocytes / Group IB Phospholipases A2 / Receptors, Phospholipase A2 / TOR Serine-Threonine Kinases / Autophagy-Related Protein-1 Homolog Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2021 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: Autophagy / Glomerulonephritis, Membranous / MAP Kinase Signaling System / P38 Mitogen-Activated Protein Kinases / Intracellular Signaling Peptides and Proteins / Podocytes / Group IB Phospholipases A2 / Receptors, Phospholipase A2 / TOR Serine-Threonine Kinases / Autophagy-Related Protein-1 Homolog Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2021 Type: Article Affiliation country: China