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Detection of Pathogenic Variants With Germline Genetic Testing Using Deep Learning vs Standard Methods in Patients With Prostate Cancer and Melanoma.
AlDubayan, Saud H; Conway, Jake R; Camp, Sabrina Y; Witkowski, Leora; Kofman, Eric; Reardon, Brendan; Han, Seunghun; Moore, Nicholas; Elmarakeby, Haitham; Salari, Keyan; Choudhry, Hani; Al-Rubaish, Abdullah M; Al-Sulaiman, Abdulsalam A; Al-Ali, Amein K; Taylor-Weiner, Amaro; Van Allen, Eliezer M.
Affiliation
  • AlDubayan SH; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Harvard University, Boston, Massachusetts.
  • Conway JR; Cancer Program, Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge.
  • Camp SY; Division of Genetics, Brigham and Women's Hospital, Boston, Massachusetts.
  • Witkowski L; College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
  • Kofman E; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Harvard University, Boston, Massachusetts.
  • Reardon B; Cancer Program, Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge.
  • Han S; Division of Medical Sciences, Department of Biomedical Informatics, Harvard University, Boston, Massachusetts.
  • Moore N; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Harvard University, Boston, Massachusetts.
  • Elmarakeby H; Cancer Program, Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge.
  • Salari K; Genetics Training Program, Harvard Medical School, Harvard University, Boston, Massachusetts.
  • Choudhry H; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Harvard University, Boston, Massachusetts.
  • Al-Rubaish AM; Cancer Program, Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge.
  • Al-Sulaiman AA; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Harvard University, Boston, Massachusetts.
  • Al-Ali AK; Cancer Program, Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge.
  • Taylor-Weiner A; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Harvard University, Boston, Massachusetts.
  • Van Allen EM; Cancer Program, Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge.
JAMA ; 324(19): 1957-1969, 2020 11 17.
Article in En | MEDLINE | ID: mdl-33201204
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Full text: 1 Database: MEDLINE Main subject: Prostatic Neoplasms / DNA Mutational Analysis / Genetic Testing / Germ-Line Mutation / Deep Learning / Melanoma Type of study: Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: JAMA Year: 2020 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Prostatic Neoplasms / DNA Mutational Analysis / Genetic Testing / Germ-Line Mutation / Deep Learning / Melanoma Type of study: Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: JAMA Year: 2020 Type: Article