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Functional inhibition or genetic deletion of acid sphingomyelinase bacteriostatically inhibits Anaplasma phagocytophilum infection in vivo.
Naimi, Waheeda A; Gumpf, Jacob J; Cockburn, Chelsea L; Camus, Sarah; Chalfant, Charles E; Li, Pin-Lan; Carlyon, Jason A.
Affiliation
  • Naimi WA; Department of Microbiology and Immunology, Virginia Commonwealth University (VCU) Medical Center, VCU School of Medicine, Richmond, VA, 23398 USA.
  • Gumpf JJ; Department of Microbiology and Immunology, Virginia Commonwealth University (VCU) Medical Center, VCU School of Medicine, Richmond, VA, 23398 USA.
  • Cockburn CL; Department of Microbiology and Immunology, Virginia Commonwealth University (VCU) Medical Center, VCU School of Medicine, Richmond, VA, 23398 USA.
  • Camus S; Department of Pharmacology and Toxicology, Virginia Commonwealth University (VCU) Medical Center, VCU School of Medicine, Richmond, VA, 23298 USA.
  • Chalfant CE; Department of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, FL,33620 USA.
  • Li PL; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University (VCU), Richmond, VA 23298, USA.
  • Carlyon JA; The Moffitt Cancer Center, Tampa, FL 33620, USA.
Pathog Dis ; 79(1)2021 01 06.
Article in En | MEDLINE | ID: mdl-33220685
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Full text: 1 Database: MEDLINE Main subject: Sphingomyelin Phosphodiesterase / Anaplasma phagocytophilum / Desipramine / Anaplasmosis Limits: Animals / Female / Humans / Male Language: En Journal: Pathog Dis Year: 2021 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Sphingomyelin Phosphodiesterase / Anaplasma phagocytophilum / Desipramine / Anaplasmosis Limits: Animals / Female / Humans / Male Language: En Journal: Pathog Dis Year: 2021 Type: Article