Heterozygosity of murine Crkl does not recapitulate behavioral dimensions of human 22q11.2 hemizygosity.

Yamauchi, Takahira; Kang, Gina; Hiroi, Noboru

Yamauchi, Takahira; Kang, Gina; Hiroi, Noboru.

Affiliation

Yamauchi T; Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Kang G; Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Hiroi N; Department of Pharmacology, University of Texas Health Science Center at San Antonio, San Antonio, Texas.

Genes Brain Behav ; 20(5): e12719, 2021 06.

Article in En | MEDLINE | ID: mdl-33269541

Subject(s)

Adaptor Proteins, Signal Transducing/genetics; DiGeorge Syndrome/genetics; Motor Activity; Open Field Test; Social Behavior; Animals; Gene Deletion; Heterozygote; Male; Mice; Mice, Inbred C57BL; Phenotype

Key words

22q11.2; CNV; Crkl; anxiety; autism; intellectual disability; motor activity; schizophrenia; social behavior; working memory

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Full text: 1 Database: MEDLINE Main subject: Social Behavior / Adaptor Proteins, Signal Transducing / DiGeorge Syndrome / Open Field Test / Motor Activity Limits: Animals Language: En Journal: Genes Brain Behav Journal subject: CIENCIAS DO COMPORTAMENTO / GENETICA Year: 2021 Type: Article

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