Argonaute NRDE-3 and MBT domain protein LIN-61 redundantly recruit an H3K9me3 HMT to prevent embryonic lethality and transposon expression.

Padeken, Jan; Methot, Stephen; Zeller, Peter; Delaney, Colin E; Kalck, Veronique; Gasser, Susan M

Padeken, Jan; Methot, Stephen; Zeller, Peter; Delaney, Colin E; Kalck, Veronique; Gasser, Susan M.

Affiliation

Padeken J; Friedrich Miescher Institute for Biomedical Research, CH-4058 Basel, Switzerland.
Methot S; Friedrich Miescher Institute for Biomedical Research, CH-4058 Basel, Switzerland.
Zeller P; Friedrich Miescher Institute for Biomedical Research, CH-4058 Basel, Switzerland.
Delaney CE; Faculty of Natural Sciences, University of Basel, CH-4056 Basel, Switzerland.
Kalck V; Friedrich Miescher Institute for Biomedical Research, CH-4058 Basel, Switzerland.
Gasser SM; Friedrich Miescher Institute for Biomedical Research, CH-4058 Basel, Switzerland.

Genes Dev ; 35(1-2): 82-101, 2021 01 01.

Article in En | MEDLINE | ID: mdl-33303642

Subject(s)

Caenorhabditis elegans Proteins/metabolism; Caenorhabditis elegans/genetics; Chromosomal Proteins, Non-Histone/metabolism; DNA Transposable Elements/genetics; Gene Expression Regulation/genetics; Heterochromatin/genetics; RNA-Binding Proteins/metabolism; Animals; Caenorhabditis elegans Proteins/genetics; Chromosomal Proteins, Non-Histone/genetics; Embryo, Nonmammalian; Gene Silencing; Heterochromatin/metabolism; Histone-Lysine N-Methyltransferase/genetics; Histone-Lysine N-Methyltransferase/metabolism; Histones/metabolism; Methylation; Mutation; RNA-Binding Proteins/genetics

Key words

Argonaute; HMT; LIN-61; MBT domain proteins; MET-2; NRDE-3; SET-25; heterochromatin; histone methyltransferases (HMTs); transposon silencing

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Full text: 1 Database: MEDLINE Main subject: Chromosomal Proteins, Non-Histone / DNA Transposable Elements / Heterochromatin / Gene Expression Regulation / RNA-Binding Proteins / Caenorhabditis elegans / Caenorhabditis elegans Proteins Limits: Animals Language: En Journal: Genes Dev Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article Affiliation country: Switzerland

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