Overview of Targets and Potential Drugs of SARS-CoV-2 According to the Viral Replication.

Zhang, Yi; Tang, Liang V

Zhang, Yi; Tang, Liang V.

Affiliation

Zhang Y; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Tang LV; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

J Proteome Res ; 20(1): 49-59, 2021 01 01.

Article in En | MEDLINE | ID: mdl-33347311

Subject(s)

Antiviral Agents/pharmacology; SARS-CoV-2/drug effects; Virus Replication/drug effects; Angiotensin-Converting Enzyme 2/metabolism; Animals; Antiviral Agents/chemistry; Basigin/metabolism; Coronavirus 3C Proteases/antagonists & inhibitors; Coronavirus 3C Proteases/metabolism; Coronavirus Nucleocapsid Proteins/chemistry; Coronavirus Nucleocapsid Proteins/metabolism; Coronavirus RNA-Dependent RNA Polymerase/metabolism; Dipeptidyl Peptidase 4/metabolism; Furin/antagonists & inhibitors; Furin/metabolism; Host-Pathogen Interactions/drug effects; Humans; SARS-CoV-2/pathogenicity; SARS-CoV-2/physiology; Serine Endopeptidases/metabolism; Small Molecule Libraries/pharmacology; Spike Glycoprotein, Coronavirus/chemistry; Spike Glycoprotein, Coronavirus/metabolism

Key words

SARS-CoV-2; drug; replication process; target

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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / Virus Replication / SARS-CoV-2 Limits: Animals / Humans Language: En Journal: J Proteome Res Journal subject: BIOQUIMICA Year: 2021 Type: Article Affiliation country: China

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