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Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration.
Fukuda, Shinichi; Varshney, Akhil; Fowler, Benjamin J; Wang, Shao-Bin; Narendran, Siddharth; Ambati, Kameshwari; Yasuma, Tetsuhiro; Magagnoli, Joseph; Leung, Hannah; Hirahara, Shuichiro; Nagasaka, Yosuke; Yasuma, Reo; Apicella, Ivana; Pereira, Felipe; Makin, Ryan D; Magner, Eamonn; Liu, Xinan; Sun, Jian; Wang, Mo; Baker, Kirstie; Marion, Kenneth M; Huang, Xiwen; Baghdasaryan, Elmira; Ambati, Meenakshi; Ambati, Vidya L; Pandey, Akshat; Pandya, Lekha; Cummings, Tammy; Banerjee, Daipayan; Huang, Peirong; Yerramothu, Praveen; Tolstonog, Genrich V; Held, Ulrike; Erwin, Jennifer A; Paquola, Apua C M; Herdy, Joseph R; Ogura, Yuichiro; Terasaki, Hiroko; Oshika, Tetsuro; Darwish, Shaban; Singh, Ramendra K; Mozaffari, Saghar; Bhattarai, Deepak; Kim, Kyung Bo; Hardin, James W; Bennett, Charles L; Hinton, David R; Hanson, Timothy E; Röver, Christian; Parang, Keykavous.
Affiliation
  • Fukuda S; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Varshney A; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Fowler BJ; Department of Ophthalmology, University of Tsukuba, Ibaraki 305-8575, Japan.
  • Wang SB; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Narendran S; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Ambati K; Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY 40536.
  • Yasuma T; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Magagnoli J; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Leung H; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Hirahara S; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Nagasaka Y; Aravind Eye Hospital System, Madurai 625020, India.
  • Yasuma R; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Apicella I; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Pereira F; Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY 40536.
  • Makin RD; Department of Ophthalmology, Graduate School of Medicine, Nagoya University, Nagoya 464-8601, Japan.
  • Magner E; Dorn Research Institute, Columbia Veterans Affairs Health Care System, Columbia, SC 29209.
  • Liu X; Department of Clinical Pharmacy and Outcomes Sciences, College of Pharmacy, University of South Carolina, Columbia, SC 29208.
  • Sun J; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Wang M; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Baker K; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Marion KM; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Huang X; Department of Ophthalmology, Graduate School of Medical Sciences, Nagoya City University, Nagoya 467-8601, Japan.
  • Baghdasaryan E; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Ambati M; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Ambati VL; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Pandey A; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Pandya L; Department of Ophthalmology, Graduate School of Medicine, Nagoya University, Nagoya 464-8601, Japan.
  • Cummings T; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Banerjee D; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Huang P; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Yerramothu P; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Tolstonog GV; Departamento de Oftalmologia e Ciências Visuais, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo 04023-062, Brazil.
  • Held U; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Erwin JA; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Paquola ACM; Department of Computer Science, University of Kentucky, Lexington, KY 40536.
  • Herdy JR; Department of Computer Science, University of Kentucky, Lexington, KY 40536.
  • Ogura Y; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Terasaki H; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Oshika T; Doheny Eye Institute, Los Angeles, CA 90033.
  • Darwish S; Doheny Eye Institute, Los Angeles, CA 90033.
  • Singh RK; Doheny Eye Institute, Los Angeles, CA 90033.
  • Mozaffari S; Department of Computer Science, University of Kentucky, Lexington, KY 40536.
  • Bhattarai D; Doheny Eye Institute, Los Angeles, CA 90033.
  • Kim KB; Department of Ophthalmology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095.
  • Hardin JW; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Bennett CL; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Hinton DR; Center for Digital Image Evaluation, Charlottesville, VA 22901.
  • Hanson TE; Center for Digital Image Evaluation, Charlottesville, VA 22901.
  • Röver C; Center for Advanced Vision Science, School of Medicine, University of Virginia, Charlottesville, VA 22908.
  • Parang K; Department of Ophthalmology, School of Medicine, University of Virginia, Charlottesville, VA 22908.
Proc Natl Acad Sci U S A ; 118(6)2021 02 09.
Article in En | MEDLINE | ID: mdl-33526699
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Full text: 1 Database: MEDLINE Main subject: Retinal Pigments / Long Interspersed Nucleotide Elements / Alu Elements / Macular Degeneration Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Retinal Pigments / Long Interspersed Nucleotide Elements / Alu Elements / Macular Degeneration Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Type: Article