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Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization.
Liu, Zhuoming; VanBlargan, Laura A; Bloyet, Louis-Marie; Rothlauf, Paul W; Chen, Rita E; Stumpf, Spencer; Zhao, Haiyan; Errico, John M; Theel, Elitza S; Liebeskind, Mariel J; Alford, Brynn; Buchser, William J; Ellebedy, Ali H; Fremont, Daved H; Diamond, Michael S; Whelan, Sean P J.
Affiliation
  • Liu Z; Department of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • VanBlargan LA; Department of Medicine, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Bloyet LM; Department of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Rothlauf PW; Department of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA; Program in Virology, Harvard Medical School, Boston, MA, USA.
  • Chen RE; Department of Medicine, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA; Department of Pathology & Immunology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Stumpf S; Department of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Zhao H; Department of Pathology & Immunology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Errico JM; Department of Pathology & Immunology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Theel ES; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
  • Liebeskind MJ; Department of Genetics, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Alford B; Department of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Buchser WJ; Department of Genetics, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Ellebedy AH; Department of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA; Department of Pathology & Immunology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Fremont DH; Department of Pathology & Immunology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Diamond MS; Department of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA; Department of Medicine, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA; Department of Pathology & Immunology, School of Medicine, Washington University in
  • Whelan SPJ; Department of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA. Electronic address: spjwhelan@wustl.edu.
Cell Host Microbe ; 29(3): 477-488.e4, 2021 03 10.
Article in En | MEDLINE | ID: mdl-33535027
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Full text: 1 Database: MEDLINE Main subject: Neutralization Tests / Spike Glycoprotein, Coronavirus / SARS-CoV-2 / Antibodies, Monoclonal / Antibodies, Viral / Mutation Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cell Host Microbe Journal subject: MICROBIOLOGIA Year: 2021 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Neutralization Tests / Spike Glycoprotein, Coronavirus / SARS-CoV-2 / Antibodies, Monoclonal / Antibodies, Viral / Mutation Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cell Host Microbe Journal subject: MICROBIOLOGIA Year: 2021 Type: Article Affiliation country: United States