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Novel Lesional Transcriptional Signature Separates Atherosclerosis With and Without Diabetes in Yorkshire Swine and Humans.
Haemmig, Stefan; Hashemi Gheinani, Ali; Zaromytidou, Marina; Siasos, Gerasimos; Coskun, Ahmet Umit; Cormier, Michelle A; Gross, David A; Wara, A K M Khyrul; Antoniadis, Antonios P; Sun, Xinghui; Sukhova, Galina K; Welt, Fred G P; Andreou, Ioannis; Whatling, Carl; Gan, Li-Ming; Wikström, Johannes; Edelman, Elazer R; Libby, Peter; Stone, Peter H; Feinberg, Mark W.
Affiliation
  • Haemmig S; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital (S.H., M.Z., G.S., A.U.C., M.A.C., D.A.G., A.K.W., A.P.A., X.S., G.K.S., I.A., E.R.E., P.L., P.H.S., M.W.F.), Harvard Medical School, Boston, MA.
  • Hashemi Gheinani A; Department of Surgery, Urological Diseases Research Center, Boston Children Hospital (A.H.G.), Harvard Medical School, Boston, MA.
  • Zaromytidou M; Broad Institute of MIT and Harvard, Cambridge, MA (A.H.G.).
  • Siasos G; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital (S.H., M.Z., G.S., A.U.C., M.A.C., D.A.G., A.K.W., A.P.A., X.S., G.K.S., I.A., E.R.E., P.L., P.H.S., M.W.F.), Harvard Medical School, Boston, MA.
  • Coskun AU; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital (S.H., M.Z., G.S., A.U.C., M.A.C., D.A.G., A.K.W., A.P.A., X.S., G.K.S., I.A., E.R.E., P.L., P.H.S., M.W.F.), Harvard Medical School, Boston, MA.
  • Cormier MA; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital (S.H., M.Z., G.S., A.U.C., M.A.C., D.A.G., A.K.W., A.P.A., X.S., G.K.S., I.A., E.R.E., P.L., P.H.S., M.W.F.), Harvard Medical School, Boston, MA.
  • Gross DA; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital (S.H., M.Z., G.S., A.U.C., M.A.C., D.A.G., A.K.W., A.P.A., X.S., G.K.S., I.A., E.R.E., P.L., P.H.S., M.W.F.), Harvard Medical School, Boston, MA.
  • Wara AKMK; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital (S.H., M.Z., G.S., A.U.C., M.A.C., D.A.G., A.K.W., A.P.A., X.S., G.K.S., I.A., E.R.E., P.L., P.H.S., M.W.F.), Harvard Medical School, Boston, MA.
  • Antoniadis AP; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital (S.H., M.Z., G.S., A.U.C., M.A.C., D.A.G., A.K.W., A.P.A., X.S., G.K.S., I.A., E.R.E., P.L., P.H.S., M.W.F.), Harvard Medical School, Boston, MA.
  • Sun X; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital (S.H., M.Z., G.S., A.U.C., M.A.C., D.A.G., A.K.W., A.P.A., X.S., G.K.S., I.A., E.R.E., P.L., P.H.S., M.W.F.), Harvard Medical School, Boston, MA.
  • Sukhova GK; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital (S.H., M.Z., G.S., A.U.C., M.A.C., D.A.G., A.K.W., A.P.A., X.S., G.K.S., I.A., E.R.E., P.L., P.H.S., M.W.F.), Harvard Medical School, Boston, MA.
  • Welt FGP; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital (S.H., M.Z., G.S., A.U.C., M.A.C., D.A.G., A.K.W., A.P.A., X.S., G.K.S., I.A., E.R.E., P.L., P.H.S., M.W.F.), Harvard Medical School, Boston, MA.
  • Andreou I; Division of Cardiovascular Medicine, University of Utah Health Sciences Center, Salt Lake City (F.G.P.W.).
  • Whatling C; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital (S.H., M.Z., G.S., A.U.C., M.A.C., D.A.G., A.K.W., A.P.A., X.S., G.K.S., I.A., E.R.E., P.L., P.H.S., M.W.F.), Harvard Medical School, Boston, MA.
  • Gan LM; Bioscience Cardiovascular/Early Clinical Development/Translational Science and Experimental Medicine, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden (C.W., L.-M.G., J.W.).
  • Wikström J; Bioscience Cardiovascular/Early Clinical Development/Translational Science and Experimental Medicine, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden (C.W., L.-M.G., J.W.).
  • Libby P; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital (S.H., M.Z., G.S., A.U.C., M.A.C., D.A.G., A.K.W., A.P.A., X.S., G.K.S., I.A., E.R.E., P.L., P.H.S., M.W.F.), Harvard Medical School, Boston, MA.
  • Stone PH; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge (E.R.E.).
  • Feinberg MW; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital (S.H., M.Z., G.S., A.U.C., M.A.C., D.A.G., A.K.W., A.P.A., X.S., G.K.S., I.A., E.R.E., P.L., P.H.S., M.W.F.), Harvard Medical School, Boston, MA.
Arterioscler Thromb Vasc Biol ; 41(4): 1487-1503, 2021 04.
Article in En | MEDLINE | ID: mdl-33567868
ABSTRACT
[Figure see text].
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Full text: 1 Database: MEDLINE Main subject: Coronary Artery Disease / Carotid Artery Diseases / Gene Expression Profiling / Diabetes Mellitus, Type 2 / Plaque, Atherosclerotic / Transcriptome Type of study: Diagnostic_studies Limits: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2021 Type: Article Affiliation country: Morocco
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Full text: 1 Database: MEDLINE Main subject: Coronary Artery Disease / Carotid Artery Diseases / Gene Expression Profiling / Diabetes Mellitus, Type 2 / Plaque, Atherosclerotic / Transcriptome Type of study: Diagnostic_studies Limits: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2021 Type: Article Affiliation country: Morocco