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Plant-derived isoquinoline alkaloids that target ergosterol biosynthesis discovered by using a novel antifungal screening tool.
Wong-Deyrup, Siu Wah; Song, Xun; Ng, Tsz-Wai; Liu, Xiu-Bin; Zeng, Jian-Guo; Qing, Zhi-Xing; Deyrup, Stephen T; He, Zhen-Dan; Zhang, Hong-Jie.
Affiliation
  • Wong-Deyrup SW; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, PR China.
  • Song X; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, PR China; School of Pharmaceutical Science, Health Science Center, Shenzhen University, Shenzhen, PR China.
  • Ng TW; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, PR China.
  • Liu XB; Hunan Provincial Key Laboratory of Crop Germplasm Innovation and Utilization and National Chinese Medicinal Herbs Hunan Technology Center, Hunan Agricultural University, Changsha 410128, PR China; Hunan Co-Innovation Center for Utilization of Botanicals Functional Ingredients, Hunan University of Ch
  • Zeng JG; Hunan Provincial Key Laboratory of Crop Germplasm Innovation and Utilization and National Chinese Medicinal Herbs Hunan Technology Center, Hunan Agricultural University, Changsha 410128, PR China; Hunan Co-Innovation Center for Utilization of Botanicals Functional Ingredients, Hunan University of Ch
  • Qing ZX; Hunan Provincial Key Laboratory of Crop Germplasm Innovation and Utilization and National Chinese Medicinal Herbs Hunan Technology Center, Hunan Agricultural University, Changsha 410128, PR China; Hunan Co-Innovation Center for Utilization of Botanicals Functional Ingredients, Hunan University of Ch
  • Deyrup ST; Department of Chemistry and Biochemistry, Siena College, Loudonville, NY 12211, USA.
  • He ZD; School of Pharmaceutical Science, Health Science Center, Shenzhen University, Shenzhen, PR China; College of Pharmacy, Shenzhen Technology University, Shenzhen 518118, China. Electronic address: hezhendan@sztu.edu.cn.
  • Zhang HJ; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, PR China. Electronic address: zhanghj@hkbu.edu.hk.
Biomed Pharmacother ; 137: 111348, 2021 May.
Article in En | MEDLINE | ID: mdl-33578237

Full text: 1 Database: MEDLINE Main subject: Alkaloids / Ergosterol / High-Throughput Screening Assays / Isoquinolines / Antifungal Agents Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Animals Language: En Journal: Biomed Pharmacother Year: 2021 Type: Article

Full text: 1 Database: MEDLINE Main subject: Alkaloids / Ergosterol / High-Throughput Screening Assays / Isoquinolines / Antifungal Agents Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Animals Language: En Journal: Biomed Pharmacother Year: 2021 Type: Article