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CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumours.
Zappasodi, Roberta; Serganova, Inna; Cohen, Ivan J; Maeda, Masatomo; Shindo, Masahiro; Senbabaoglu, Yasin; Watson, McLane J; Leftin, Avigdor; Maniyar, Rachana; Verma, Svena; Lubin, Matthew; Ko, Myat; Mane, Mayuresh M; Zhong, Hong; Liu, Cailian; Ghosh, Arnab; Abu-Akeel, Mohsen; Ackerstaff, Ellen; Koutcher, Jason A; Ho, Ping-Chih; Delgoffe, Greg M; Blasberg, Ronald; Wolchok, Jedd D; Merghoub, Taha.
Affiliation
  • Zappasodi R; Ludwig Collaborative and Swim Across America Laboratory, MSK, New York, NY, USA. roz4002@med.cornell.edu.
  • Serganova I; Parker Institute for Cancer Immunotherapy, MSK, New York, NY, USA. roz4002@med.cornell.edu.
  • Cohen IJ; Weill Cornell Medicine, New York, NY, USA. roz4002@med.cornell.edu.
  • Maeda M; Weill Cornell Medicine, New York, NY, USA.
  • Shindo M; Department of Neurology, MSK, New York, NY, USA.
  • Senbabaoglu Y; Department of Neurology, MSK, New York, NY, USA.
  • Watson MJ; Gerstner Sloan Kettering Graduate School of Biomedical Sciences, MSK, New York, NY, USA.
  • Leftin A; Department of Neurology, MSK, New York, NY, USA.
  • Maniyar R; Department of Neurology, MSK, New York, NY, USA.
  • Verma S; Ludwig Collaborative and Swim Across America Laboratory, MSK, New York, NY, USA.
  • Lubin M; Department of Oncology Bioinformatics, Genentech, South San Francisco, CA, USA.
  • Ko M; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.
  • Mane MM; Department of Medical Physics, MSK, New York, NY, USA.
  • Zhong H; Ludwig Collaborative and Swim Across America Laboratory, MSK, New York, NY, USA.
  • Liu C; Ludwig Collaborative and Swim Across America Laboratory, MSK, New York, NY, USA.
  • Ghosh A; Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, NY, USA.
  • Abu-Akeel M; Department of Neurology, MSK, New York, NY, USA.
  • Ackerstaff E; Department of Neurology, MSK, New York, NY, USA.
  • Koutcher JA; Department of Neurology, MSK, New York, NY, USA.
  • Ho PC; Ludwig Collaborative and Swim Across America Laboratory, MSK, New York, NY, USA.
  • Delgoffe GM; Ludwig Collaborative and Swim Across America Laboratory, MSK, New York, NY, USA.
  • Blasberg R; Ludwig Collaborative and Swim Across America Laboratory, MSK, New York, NY, USA.
  • Wolchok JD; Ludwig Collaborative and Swim Across America Laboratory, MSK, New York, NY, USA.
  • Merghoub T; Department of Medical Physics, MSK, New York, NY, USA.
Nature ; 591(7851): 652-658, 2021 03.
Article in En | MEDLINE | ID: mdl-33588426
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Full text: 1 Database: MEDLINE Main subject: T-Lymphocytes, Regulatory / CTLA-4 Antigen / Glycolysis / Neoplasms Limits: Animals / Female / Humans Language: En Journal: Nature Year: 2021 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: T-Lymphocytes, Regulatory / CTLA-4 Antigen / Glycolysis / Neoplasms Limits: Animals / Female / Humans Language: En Journal: Nature Year: 2021 Type: Article Affiliation country: United States