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Exploring the Chemistry of Alkaloids from Malaysian Mitragyna speciosa (Kratom) and the Role of Oxindoles on Human Opioid Receptors.
Chear, Nelson Jeng-Yeou; León, Francisco; Sharma, Abhisheak; Kanumuri, Siva Rama Raju; Zwolinski, Grant; Abboud, Khalil A; Singh, Darshan; Restrepo, Luis F; Patel, Avi; Hiranita, Takato; Ramanathan, Surash; Hampson, Aidan J; McMahon, Lance R; McCurdy, Christopher R.
Affiliation
  • Chear NJ; Centre for Drug Research, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia.
  • León F; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
  • Sharma A; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
  • Kanumuri SRR; Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
  • Zwolinski G; Translational Drug Development Core, Clinical and Translational Sciences Institute, University of Florida, Gainesville, Florida 32610, United States.
  • Abboud KA; Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
  • Singh D; Translational Drug Development Core, Clinical and Translational Sciences Institute, University of Florida, Gainesville, Florida 32610, United States.
  • Restrepo LF; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
  • Patel A; Department of Chemistry, University of Florida, Gainesville, Florida 32611, United States.
  • Hiranita T; Centre for Drug Research, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia.
  • Ramanathan S; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
  • Hampson AJ; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
  • McMahon LR; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
  • McCurdy CR; Centre for Drug Research, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia.
J Nat Prod ; 84(4): 1034-1043, 2021 04 23.
Article in En | MEDLINE | ID: mdl-33635670
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Full text: 1 Database: MEDLINE Main subject: Receptors, Opioid, mu / Mitragyna / Oxindoles / Analgesics Limits: Animals / Female / Humans / Male Country/Region as subject: Asia Language: En Journal: J Nat Prod Year: 2021 Type: Article Affiliation country: Malaysia
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Receptors, Opioid, mu / Mitragyna / Oxindoles / Analgesics Limits: Animals / Female / Humans / Male Country/Region as subject: Asia Language: En Journal: J Nat Prod Year: 2021 Type: Article Affiliation country: Malaysia