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Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model.
Xiong, Rui; Wu, Yue; Wu, Qiangen; Muskhelishvili, Levan; Davis, Kelly; Tripathi, Priya; Chen, Ying; Chen, Tao; Bryant, Matthew; Rosenfeldt, Hans; Healy, Sheila M; Cao, Xuefei.
Affiliation
  • Xiong R; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Wu Y; Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Wu Q; Division of Biochemical Toxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Muskhelishvili L; Toxicologic Pathology Associates, Jefferson, AR, 72079, USA.
  • Davis K; Toxicologic Pathology Associates, Jefferson, AR, 72079, USA.
  • Tripathi P; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Chen Y; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Chen T; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Bryant M; Office of Scientific Coordination, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, 72079, USA.
  • Rosenfeldt H; Division of Nonclinical Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, Maryland, 20993, USA.
  • Healy SM; Division of Nonclinical Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, Maryland, 20993, USA.
  • Cao X; Division of Genetic and Molecular Toxicology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, 72079, USA. Xuefei.cao@fda.hhs.gov.
Arch Toxicol ; 95(5): 1739-1761, 2021 05.
Article in En | MEDLINE | ID: mdl-33660061
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Full text: 1 Database: MEDLINE Main subject: Nicotiana / Tobacco Smoke Pollution / Toxicity Tests Type of study: Guideline / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Arch Toxicol Year: 2021 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Nicotiana / Tobacco Smoke Pollution / Toxicity Tests Type of study: Guideline / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Arch Toxicol Year: 2021 Type: Article Affiliation country: United States