Shape and Function of Interstitial Chemokine CCL21 Gradients Are Independent of Heparan Sulfates Produced by Lymphatic Endothelium.

Vaahtomeri, Kari; Moussion, Christine; Hauschild, Robert; Sixt, Michael

Vaahtomeri, Kari; Moussion, Christine; Hauschild, Robert; Sixt, Michael.

Affiliation

Vaahtomeri K; Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.
Moussion C; Wihuri Research Institute and Translational Cancer Medicine Research Program, University of Helsinki, Biomedicum Helsinki, Helsinki, Finland.
Hauschild R; Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.
Sixt M; Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.

Front Immunol ; 12: 630002, 2021.

Article in En | MEDLINE | ID: mdl-33717158

Subject(s)

Chemokine CCL21/metabolism; Dendritic Cells/immunology; Dermis/immunology; Endothelium, Lymphatic/immunology; Heparitin Sulfate/metabolism; Lymphatic Vessels/pathology; Animals; Cells, Cultured; Chemotaxis; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, CCR7/genetics

Key words

chemokine CCL21; chemokine gradient; chemotaxis; dendritic cell; heparan sulfate; lymphatic endothelium; lymphatic system

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Full text: 1 Database: MEDLINE Main subject: Dendritic Cells / Endothelium, Lymphatic / Dermis / Lymphatic Vessels / Chemokine CCL21 / Heparitin Sulfate Type of study: Prognostic_studies Limits: Animals Language: En Journal: Front Immunol Year: 2021 Type: Article Affiliation country: Austria

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