Addressing Antiretroviral Drug Resistance with Host-Targeting Drugs-First Steps towards Developing a Host-Targeting HIV-1 Assembly Inhibitor.

Lingappa, Jaisri R; Lingappa, Vishwanath R; Reed, Jonathan C

Lingappa, Jaisri R; Lingappa, Vishwanath R; Reed, Jonathan C.

Affiliation

Lingappa JR; Department of Global Health, University of Washington, Seattle, WA 98109, USA.
Lingappa VR; Prosetta Biosciences, 670 5th Street, San Francisco, CA 94107, USA.
Reed JC; Department of Global Health, University of Washington, Seattle, WA 98109, USA.

Viruses ; 13(3)2021 03 10.

Article in En | MEDLINE | ID: mdl-33802145

Subject(s)

Anti-Retroviral Agents/pharmacology; Drug Resistance, Viral; HIV-1/drug effects; Host Microbial Interactions/drug effects; Virus Assembly/drug effects; Anti-Retroviral Agents/isolation & purification; Capsid/metabolism; HIV Seropositivity; HIV-1/physiology; Humans; T-Lymphocytes/drug effects; T-Lymphocytes/virology

Key words

ABCE1; DDX6; Gag; HIV-1 assembly; HIV-1 capsid; RNA granule; antiretroviral; antiviral; drug screen; viral-host interactions

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Full text: 1 Database: MEDLINE Main subject: HIV-1 / Virus Assembly / Drug Resistance, Viral / Anti-Retroviral Agents / Host Microbial Interactions Limits: Humans Language: En Journal: Viruses Year: 2021 Type: Article Affiliation country: United States

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