Is the Membrane Lipid Matrix a Key Target for Action of Pharmacologically Active Plant Saponins?

Efimova, Svetlana S; Ostroumova, Olga S

Efimova, Svetlana S; Ostroumova, Olga S.

Affiliation

Efimova SS; Institute of Cytology of Russian Academy of Sciences, 199034 Saint Petersburg, Russia.
Ostroumova OS; Institute of Cytology of Russian Academy of Sciences, 199034 Saint Petersburg, Russia.

Int J Mol Sci ; 22(6)2021 Mar 20.

Article in En | MEDLINE | ID: mdl-33804648

Subject(s)

Cell Membrane/drug effects; Membrane Lipids/chemistry; Saponins/pharmacology; Cell Membrane/chemistry; Cell Membrane Permeability/drug effects; Dose-Response Relationship, Drug; Ion Channel Gating/drug effects; Ion Channels/chemistry; Ion Channels/metabolism; Lipid Bilayers/chemistry; Membrane Lipids/antagonists & inhibitors; Membrane Potentials/drug effects; Molecular Structure; Phase Transition/drug effects; Saponins/chemistry

Key words

calcein release; gramicidin A; ion channel; lipid bilayers; lipid melting; liposomes; membrane boundary potential; nystatin; saponins; syringomycin E; terpenes

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Saponins / Cell Membrane / Membrane Lipids Language: En Journal: Int J Mol Sci Year: 2021 Type: Article Affiliation country: RUSSIA

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google