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A novel anti-human IL-1R7 antibody reduces IL-18-mediated inflammatory signaling.
Li, Suzhao; Jiang, Liqiong; Beckmann, Karsten; Højen, Jesper Falkesgaard; Pessara, Ulrich; Powers, Nicholas E; de Graaf, Dennis M; Azam, Tania; Lindenberger, Jared; Eisenmesser, Elan Z; Fischer, Stephan; Dinarello, Charles A.
Affiliation
  • Li S; Department of Medicine, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA. Electronic address: suzhao.li@cuanschutz.edu.
  • Jiang L; Department of Medicine, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA; Shenzhen Eye Hospital, Shenzhen, Guangdong, China.
  • Beckmann K; MAB Discovery GmbH, Neuried, Germany.
  • Højen JF; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
  • Pessara U; MAB Discovery GmbH, Neuried, Germany.
  • Powers NE; Department of Medicine, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA.
  • de Graaf DM; Department of Medicine, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA.
  • Azam T; Department of Medicine, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA.
  • Lindenberger J; Biophysics Core Facility, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA.
  • Eisenmesser EZ; Department of Biochemistry and Molecular Genetics, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA.
  • Fischer S; MAB Discovery GmbH, Neuried, Germany.
  • Dinarello CA; Department of Medicine, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA. Electronic address: cdinare333@aol.com.
J Biol Chem ; 296: 100630, 2021.
Article in En | MEDLINE | ID: mdl-33823154
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Full text: 1 Database: MEDLINE Main subject: Interleukin-18 / Receptors, Interleukin-18 / Antibodies, Neutralizing / Immunologic Factors / Anti-Inflammatory Agents / Antibodies, Monoclonal Language: En Journal: J Biol Chem Year: 2021 Type: Article
Fulltext
Add to My VHL
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Interleukin-18 / Receptors, Interleukin-18 / Antibodies, Neutralizing / Immunologic Factors / Anti-Inflammatory Agents / Antibodies, Monoclonal Language: En Journal: J Biol Chem Year: 2021 Type: Article