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CAG RNAs induce DNA damage and apoptosis by silencing NUDT16 expression in polyglutamine degeneration.
Peng, Shaohong; Guo, Pei; Lin, Xiao; An, Ying; Sze, Kong Hung; Lau, Matthew Ho Yan; Chen, Zhefan Stephen; Wang, Qianwen; Li, Wen; Sun, Jacquelyne Ka-Li; Ma, Sum Yi; Chan, Ting-Fung; Lau, Kwok-Fai; Ngo, Jacky Chi Ki; Kwan, Kin Ming; Wong, Chun-Ho; Lam, Sik Lok; Zimmerman, Steven C; Tuccinardi, Tiziano; Zuo, Zhong; Au-Yeung, Ho Yu; Chow, Hei-Man; Chan, Ho Yin Edwin.
Affiliation
  • Peng S; Laboratory of Drosophila Research, The Chinese University of Hong Kong, Hong Kong, China.
  • Guo P; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Lin X; Department of Chemistry, The Chinese University of Hong Kong, Hong Kong, China.
  • An Y; School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, China.
  • Sze KH; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Lau MHY; Laboratory of Drosophila Research, The Chinese University of Hong Kong, Hong Kong, China.
  • Chen ZS; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Wang Q; Department of Microbiology, The University of Hong Kong, Hong Kong, China.
  • Li W; Department of Chemistry, State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Hong Kong, China.
  • Sun JK; Laboratory of Drosophila Research, The Chinese University of Hong Kong, Hong Kong, China.
  • Ma SY; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Chan TF; School of Pharmacy, The Chinese University of Hong Kong, Hong Kong, China.
  • Lau KF; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Ngo JCK; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Kwan KM; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Wong CH; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Lam SL; State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Hong Kong, China.
  • Zimmerman SC; Gerald Choa Neuroscience Centre, The Chinese University of Hong Kong, Hong Kong, China.
  • Tuccinardi T; Nexus of Rare Neurodegenerative Diseases, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Zuo Z; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Au-Yeung HY; Nexus of Rare Neurodegenerative Diseases, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Chow HM; School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China.
  • Chan HYE; State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Hong Kong, China.
Proc Natl Acad Sci U S A ; 118(19)2021 05 11.
Article in En | MEDLINE | ID: mdl-33947817
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Full text: 1 Database: MEDLINE Main subject: Peptides / Pyrophosphatases / DNA Damage / RNA / Apoptosis / Huntington Disease / Trinucleotide Repeat Expansion Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Peptides / Pyrophosphatases / DNA Damage / RNA / Apoptosis / Huntington Disease / Trinucleotide Repeat Expansion Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Type: Article Affiliation country: China