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Impaired neuronal activity and differential gene expression in STXBP1 encephalopathy patient iPSC-derived GABAergic neurons.
Ichise, Eisuke; Chiyonobu, Tomohiro; Ishikawa, Mitsuru; Tanaka, Yasuyoshi; Shibata, Mami; Tozawa, Takenori; Taura, Yoshihiro; Yamashita, Satoshi; Yoshida, Michiko; Morimoto, Masafumi; Higurashi, Norimichi; Yamamoto, Toshiyuki; Okano, Hideyuki; Hirose, Shinichi.
Affiliation
  • Ichise E; Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
  • Chiyonobu T; Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
  • Ishikawa M; Department of Physiology, Keio University School of Medicine, Tokyo 160-8582, Japan.
  • Tanaka Y; Research Institute for the Molecular Pathomechanisms of Epilepsy, Fukuoka University, Fukuoka 814-0180, Japan.
  • Shibata M; Research Institute for the Molecular Pathomechanisms of Epilepsy, Fukuoka University, Fukuoka 814-0180, Japan.
  • Tozawa T; Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
  • Taura Y; Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
  • Yamashita S; Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
  • Yoshida M; Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
  • Morimoto M; Department of Medical Science, School of Nursing, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
  • Higurashi N; Department of Pediatrics, Jikei University School of Medicine, Tokyo 105-8461, Japan.
  • Yamamoto T; Institute of Medical Genetics, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
  • Okano H; Department of Physiology, Keio University School of Medicine, Tokyo 160-8582, Japan.
  • Hirose S; Department of Pediatrics, School of Medicine, Fukuoka University, Fukuoka 814-0180, Japan.
Hum Mol Genet ; 30(14): 1337-1348, 2021 06 26.
Article in En | MEDLINE | ID: mdl-33961044
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Full text: 1 Database: MEDLINE Main subject: Brain Diseases / Induced Pluripotent Stem Cells Limits: Animals / Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2021 Type: Article Affiliation country: Japan
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Brain Diseases / Induced Pluripotent Stem Cells Limits: Animals / Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2021 Type: Article Affiliation country: Japan