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Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template.
Gordon, Calvin J; Tchesnokov, Egor P; Schinazi, Raymond F; Götte, Matthias.
Affiliation
  • Gordon CJ; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada.
  • Tchesnokov EP; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada.
  • Schinazi RF; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Center for AIDS Research, Emory University School of Medicine, and Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
  • Götte M; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada; Li Ka Shing Institute of Virology at University of Alberta, Edmonton, Alberta, Canada. Electronic address: gotte@ualberta.ca.
J Biol Chem ; 297(1): 100770, 2021 07.
Article in En | MEDLINE | ID: mdl-33989635
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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / RNA, Viral / Cytidine / SARS-CoV-2 / COVID-19 / Hydroxylamines Limits: Humans Language: En Journal: J Biol Chem Year: 2021 Type: Article Affiliation country: Canada
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / RNA, Viral / Cytidine / SARS-CoV-2 / COVID-19 / Hydroxylamines Limits: Humans Language: En Journal: J Biol Chem Year: 2021 Type: Article Affiliation country: Canada