Prognostic value of late gadolinium enhancement in arrhythmogenic right ventricular cardiomyopathy: a meta-analysis.
Clin Radiol
; 76(8): 628.e9-628.e15, 2021 08.
Article
in En
| MEDLINE
| ID: mdl-34024635
ABSTRACT
AIM:
To assess systematically the prognostic value of cardiac magnetic resonance imaging (CMRI) in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC). MATERIALS ANDMETHODS:
The full text of studies of the clinical efficacy of late gadolinium enhancement (LGE) in ARVC was retrieved in multiple databases. Stata 14 was adopted for meta-analysis and bias analysis. Heterogeneity was assessed with the I2 statistic.RESULTS:
After exclusions, 561 patients were included in five studies, and the eligibility criteria were met. The meta-analysis suggested that there was a significant difference between LGE positive and negative patients with ARVC in all-cause mortality (relative risk [RR] = 4.78, 95% confidence interval [CI] = 1.41, 16.23, p=0.012; p for heterogeneity = 0.692, I2 = 0%); major adverse cardiovascular events (MACE) (RR=2.48, 95% CI = 1.24, 4.96, p=0.010; p for heterogeneity = 0.596, I2 = 0%); ventricular tachycardia (RR=3.13, 95% CI = 1.69, 5.78, p<0.001; p for heterogeneity = 0.825, I2 = 0%); implanted cardiac defibrillators (RR=3.15, 95% CI = 1.69, 5.87], p<0.001; p for heterogeneity = 0.353, I2 = 9.4%).CONCLUSION:
LGE in ARVC patients is a predictor of all-cause mortality and MACE.
Full text:
1
Database:
MEDLINE
Main subject:
Magnetic Resonance Imaging
/
Image Enhancement
/
Contrast Media
/
Arrhythmogenic Right Ventricular Dysplasia
/
Gadolinium
Type of study:
Etiology_studies
/
Prognostic_studies
/
Systematic_reviews
Limits:
Humans
Language:
En
Journal:
Clin Radiol
Year:
2021
Type:
Article
Affiliation country:
China