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Kaempferol alleviates corneal transplantation rejection by inhibiting NLRP3 inflammasome activation and macrophage M1 polarization via promoting autophagy.
Tian, Huiwen; Lin, Shumei; Wu, Jing; Ma, Ming; Yu, Jian; Zeng, Yuanping; Liu, Qi; Chen, Linjiang; Xu, Jing.
Affiliation
  • Tian H; Department of Ophthalmology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
  • Lin S; Department of Ophthalmology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
  • Wu J; Department of Huiqiao Medical Center, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. Electronic address: wujingsci@126.com.
  • Ma M; Department of Ophthalmology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. Electronic address: Maming658587@163.com.
  • Yu J; Department of Ophthalmology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
  • Zeng Y; Department of Ophthalmology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
  • Liu Q; Department of Ophthalmology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
  • Chen L; Department of Ophthalmology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
  • Xu J; Department of Ophthalmology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Exp Eye Res ; 208: 108627, 2021 07.
Article in En | MEDLINE | ID: mdl-34044014
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Full text: 1 Database: MEDLINE Main subject: Autophagy / Corneal Transplantation / Kaempferols / Inflammasomes / NLR Family, Pyrin Domain-Containing 3 Protein / Graft Rejection / Macrophages Limits: Animals Language: En Journal: Exp Eye Res Year: 2021 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: Autophagy / Corneal Transplantation / Kaempferols / Inflammasomes / NLR Family, Pyrin Domain-Containing 3 Protein / Graft Rejection / Macrophages Limits: Animals Language: En Journal: Exp Eye Res Year: 2021 Type: Article Affiliation country: China