The pluripotency transcription factor OCT4 represses heme oxygenase-1 gene expression.

Petrone, María Victoria; Toro, Ayelén; Vazquez Echegaray, Camila; Francia, Marcos Gabriel; Solari, Claudia; Cosentino, Maria Soledad; Vazquez, Elba; Guberman, Alejandra

Petrone, María Victoria; Toro, Ayelén; Vazquez Echegaray, Camila; Francia, Marcos Gabriel; Solari, Claudia; Cosentino, Maria Soledad; Vazquez, Elba; Guberman, Alejandra.

Affiliation

Petrone MV; Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), CONICET-UBA, Buenos Aires, Argentina.
Toro A; Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), CONICET-UBA, Buenos Aires, Argentina.
Vazquez Echegaray C; Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), CONICET-UBA, Buenos Aires, Argentina.
Francia MG; Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), CONICET-UBA, Buenos Aires, Argentina.
Solari C; Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), CONICET-UBA, Buenos Aires, Argentina.
Cosentino MS; Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), CONICET-UBA, Buenos Aires, Argentina.
Vazquez E; Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales Universidad de Buenos Aires, Buenos Aires, Argentina.
Guberman A; IQUIBICEN, CONICET-UBA, Buenos Aires, Argentina.

FEBS Lett ; 595(14): 1949-1961, 2021 07.

Article in En | MEDLINE | ID: mdl-34056710

Subject(s)

Gene Expression Regulation; Heme Oxygenase-1/genetics; Membrane Proteins/genetics; Mouse Embryonic Stem Cells/metabolism; Octamer Transcription Factor-3/genetics; Pluripotent Stem Cells/metabolism; RNA, Messenger/genetics; Animals; Benzamides/pharmacology; Cell Differentiation/drug effects; Diphenylamine/analogs & derivatives; Diphenylamine/pharmacology; Embryo, Mammalian; Green Fluorescent Proteins/genetics; Green Fluorescent Proteins/metabolism; Heme Oxygenase-1/metabolism; Luciferases/genetics; Luciferases/metabolism; Membrane Proteins/metabolism; Mice; Mouse Embryonic Stem Cells/cytology; Mouse Embryonic Stem Cells/drug effects; NIH 3T3 Cells; Nanog Homeobox Protein/antagonists & inhibitors; Nanog Homeobox Protein/genetics; Nanog Homeobox Protein/metabolism; Octamer Transcription Factor-3/antagonists & inhibitors; Octamer Transcription Factor-3/metabolism; Pluripotent Stem Cells/cytology; Pluripotent Stem Cells/drug effects; Promoter Regions, Genetic; Pyridines/pharmacology; Pyrimidines/pharmacology; RNA, Messenger/metabolism; RNA, Small Interfering/genetics; RNA, Small Interfering/metabolism; SOXB1 Transcription Factors/antagonists & inhibitors; SOXB1 Transcription Factors/genetics; SOXB1 Transcription Factors/metabolism; Signal Transduction; Transcription, Genetic

Key words

OCT4; gene modulation; heme oxygenase-1; pluripotency transcription factors; pluripotent stem cells; transcription

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Full text: 1 Database: MEDLINE Main subject: RNA, Messenger / Gene Expression Regulation / Pluripotent Stem Cells / Heme Oxygenase-1 / Octamer Transcription Factor-3 / Mouse Embryonic Stem Cells / Membrane Proteins Language: En Journal: FEBS Lett Year: 2021 Type: Article Affiliation country: Argentina

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