Exploiting epigenetic dependencies in ovarian cancer therapy.

Coughlan, Aisling Y; Testa, Giuseppe

Coughlan, Aisling Y; Testa, Giuseppe.

Affiliation

Coughlan AY; Department of Experimental Oncology, European Institute of Oncology, IRCCS, Milan, Italy.
Testa G; Department of Experimental Oncology, European Institute of Oncology, IRCCS, Milan, Italy.

Int J Cancer ; 149(10): 1732-1743, 2021 11 15.

Article in En | MEDLINE | ID: mdl-34213777

Subject(s)

Epigenesis, Genetic; Epigenomics/methods; Gene Expression Regulation, Neoplastic; Ovarian Neoplasms/genetics; DNA Helicases/genetics; DNA-Binding Proteins/genetics; Enhancer of Zeste Homolog 2 Protein/genetics; Female; Humans; Nuclear Proteins/genetics; Ovarian Neoplasms/pathology; Ovarian Neoplasms/therapy; Protein-Arginine N-Methyltransferases/genetics; Transcription Factors/genetics

Key words

chromatin remodeling; disease modeling; epigenetic drugs; ovarian cancer; precision oncology

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Full text: 1 Database: MEDLINE Main subject: Ovarian Neoplasms / Gene Expression Regulation, Neoplastic / Epigenesis, Genetic / Epigenomics Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Int J Cancer Year: 2021 Type: Article Affiliation country: Italy

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