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Beyond factor H: The impact of genetic-risk variants for age-related macular degeneration on circulating factor-H-like 1 and factor-H-related protein concentrations.
Cipriani, Valentina; Tierney, Anna; Griffiths, John R; Zuber, Verena; Sergouniotis, Panagiotis I; Yates, John R W; Moore, Anthony T; Bishop, Paul N; Clark, Simon J; Unwin, Richard D.
Affiliation
  • Cipriani V; William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, United Kingdom; UCL Institute of Ophthalmology, University College London, London, EC1V 9EL, United Kingdom; Moorfields Eye Hospital National Health Service Foundation Trust, London, EC1V 2PD, United Kingdom; UCL G
  • Tierney A; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine, and Health, The University of Manchester, Manchester, M13 9NY, United Kingdom.
  • Griffiths JR; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine, and Health, The University of Manchester, Manchester, M13 9NY, United Kingdom.
  • Zuber V; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, United Kingdom.
  • Sergouniotis PI; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, M13 9PT, United Kingdom; Manchester Centre for Genomic Medicine, Saint Mary's Hospital, Manchester University National Health Service Foundation
  • Yates JRW; UCL Institute of Ophthalmology, University College London, London, EC1V 9EL, United Kingdom; Moorfields Eye Hospital National Health Service Foundation Trust, London, EC1V 2PD, United Kingdom; Department of Medical Genetics, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom.
  • Moore AT; UCL Institute of Ophthalmology, University College London, London, EC1V 9EL, United Kingdom; Moorfields Eye Hospital National Health Service Foundation Trust, London, EC1V 2PD, United Kingdom; Ophthalmology Department, University of California San Francisco, San Francisco, CA 94143-0730, USA.
  • Bishop PN; Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, M13 9PT, United Kingdom; Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Ma
  • Clark SJ; University Eye Clinic, Department for Ophthalmology, Eberhard Karls University of Tübingen, Tübingen, Baden-Württemberg, 72076, Germany; Institute for Ophthalmic Research, Eberhard Karls University of Tübingen, Tübingen, Baden-Württemberg, 72076, Germany; Lydia Becker Institute of Immunology and Inf
  • Unwin RD; Stoller Biomarker Discovery Centre and Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine, and Health, The University of Manchester, Manchester, M13 9NQ, United Kingdom. Electronic address: r.unwin@manchester.ac.uk.
Am J Hum Genet ; 108(8): 1385-1400, 2021 08 05.
Article in En | MEDLINE | ID: mdl-34260948
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Full text: 1 Database: MEDLINE Main subject: Complement C3b Inactivator Proteins / Complement Factor H / Genetic Predisposition to Disease / Polymorphism, Single Nucleotide / Macular Degeneration Type of study: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male Language: En Journal: Am J Hum Genet Year: 2021 Type: Article
Fulltext
Add to My VHL
Print
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Full text: 1 Database: MEDLINE Main subject: Complement C3b Inactivator Proteins / Complement Factor H / Genetic Predisposition to Disease / Polymorphism, Single Nucleotide / Macular Degeneration Type of study: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male Language: En Journal: Am J Hum Genet Year: 2021 Type: Article