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Massively parallel characterization of CYP2C9 variant enzyme activity and abundance.
Amorosi, Clara J; Chiasson, Melissa A; McDonald, Matthew G; Wong, Lai Hong; Sitko, Katherine A; Boyle, Gabriel; Kowalski, John P; Rettie, Allan E; Fowler, Douglas M; Dunham, Maitreya J.
Affiliation
  • Amorosi CJ; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.
  • Chiasson MA; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.
  • McDonald MG; Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA.
  • Wong LH; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.
  • Sitko KA; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.
  • Boyle G; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.
  • Kowalski JP; Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA.
  • Rettie AE; Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA.
  • Fowler DM; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA; Department of Bioengineering, University of Washington, Seattle, WA 98195, USA. Electronic address: dfowler@uw.edu.
  • Dunham MJ; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA. Electronic address: maitreya@uw.edu.
Am J Hum Genet ; 108(9): 1735-1751, 2021 09 02.
Article in En | MEDLINE | ID: mdl-34314704
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Full text: 1 Database: MEDLINE Main subject: Saccharomyces cerevisiae / Xenobiotics / Mutation, Missense / Prescription Drugs / Cytochrome P-450 CYP2C9 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Am J Hum Genet Year: 2021 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Saccharomyces cerevisiae / Xenobiotics / Mutation, Missense / Prescription Drugs / Cytochrome P-450 CYP2C9 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Am J Hum Genet Year: 2021 Type: Article Affiliation country: United States