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The anti-dysenteric drug fraxetin enhances anti-tumor efficacy of gemcitabine and suppresses pancreatic cancer development by antagonizing STAT3 activation.
Guo, Yangyang; Xiao, Yanyi; Guo, Hangcheng; Zhu, Hengyue; Chen, Dong; Wang, Jilong; Deng, Junjie; Lan, Junjie; Liu, Xiaodong; Zhang, Qiyu; Bai, Yongheng.
Affiliation
  • Guo Y; Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
  • Xiao Y; Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
  • Guo H; Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
  • Zhu H; Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
  • Chen D; The Sixth People's Hospital of Wenzhou City, Wenzhou 325000, China.
  • Wang J; Engineering Research Center of Clinical Functional Materials and Diagnosis and Treatment Devices of Zhejiang Province, Wenzhou Institute, University of Chinese Academy Sciences, Wenzhou 325000, China.
  • Deng J; Engineering Research Center of Clinical Functional Materials and Diagnosis and Treatment Devices of Zhejiang Province, Wenzhou Institute, University of Chinese Academy Sciences, Wenzhou 325000, China.
  • Lan J; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen 361000, China.
  • Liu X; Platform for Radiation Protection and Emergency Preparedness, School of Public Health and Management, Wenzhou Medical University, Wenzhou 325000, China.
  • Zhang Q; Center for Health Assessment, Wenzhou Medical University, Wenzhou 325000, China.
  • Bai Y; Department for Hepatopancreatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Aging (Albany NY) ; 13(14): 18545-18563, 2021 07 28.
Article in En | MEDLINE | ID: mdl-34320467
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Full text: 1 Database: MEDLINE Main subject: Pancreatic Neoplasms / Signal Transduction / Coumarins / Deoxycytidine / STAT3 Transcription Factor Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Aging (Albany NY) Journal subject: GERIATRIA Year: 2021 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: Pancreatic Neoplasms / Signal Transduction / Coumarins / Deoxycytidine / STAT3 Transcription Factor Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Aging (Albany NY) Journal subject: GERIATRIA Year: 2021 Type: Article Affiliation country: China